Good news for treating HIV and tuberculosis co-infection?
Related Articles
- Later Initiation of Antiretroviral Therapy in Certain TB Patients May Be Beneficial. Friswell, Andrea C. // Pulmonary Reviews;Dec2011, Vol. 16 Issue 12, p8
The article discusses a study which reveals that patients with both tuberculosis (TB) and HIV and have a CD4+ T-cell count of 50 per cubic mm or higher may benefit from initiation from antiretroviral therapy (ART) during the second phase of TB treatment compared with the initial intensive...
- Systemic Immune Activation and Microbial Translocation in Dual HIV/Tuberculosis-Infected Subjects. Toossi, Zahra; Funderburg, Nicholas T.; Sirdeshmuk, Sohani; Whalen, Christopher C.; Nanteza, Maria W.; Johnson, Denise F.; Mayanja-Kizza, Harriet; Hirsch, Christina S. // Journal of Infectious Diseases;Jun2013, Vol. 207 Issue 12, p1841
Background. Systemic immune activation is a strong predictor of progression of human immunodeficiency virus type 1 (HIV-1) disease and a prominent feature of infection with Mycobacterium tuberculosis.Objective. To understand the role of systemic immune activation and microbial translocation in...
- HAART initiated at higher CD4 count slowed disease progression. // Infectious Disease News;Nov2011, Vol. 24 Issue 11, p8
The article deals with a study published in the "Archives of Internal Medicine," which found that highly active antiretroviral therapy initiated at higher CD4 cell count was associated with slower disease progression compared with a deferral strategy.
- Neuropsychological outcomes in adults commencing highly active anti-retroviral treatment in South Africa: a prospective study. // BMC Infectious Diseases;2012, Vol. 12 Issue 1, p39
The article offers information on a study conducted on the neuropsychological outcomes in adults starting highly active anti-retroviral treatment (HAART) in South Africa. It states that CD4 cell counts were extracted from laboratory records, and the use of HAART was extracted post-hoc from...
- Evaluation of HIV-1 and CD4+ T Cell Dynamic Parameters in Patients Treated with Genotypic Resistance Testing-Guided HAART. Cappuccio, Antonio; Castiglione, Filippo; Piccoli, Benedetto; Tozzi, Valerio // Current HIV Research;Jul2008, Vol. 6 Issue 4, p363
The extent of immune restoration in HIV-1 patients on antiretroviral therapy is an important marker of disease progression. In this work, we investigate the dynamics of immune reconstitution and address the question of whether the early response to antiretroviral treatments allows to predict the...
- Marginal Structural Models for Estimating the Effect of Highly Active Antiretroviral Therapy Initiation on CD4 Cell Count. Cole, Stephen R.; Hernán, Miguel A.; Margolick, Joseph B.; Cohen, Mardge H.; Robins, James M. // American Journal of Epidemiology;Sep2005, Vol. 162 Issue 5, p471
The effect of highly active antiretroviral therapy (HAART) on the evolution of CD4-positive T-lymphocyte (CD4 cell) count among human immunodeficiency virus (HIV)-positive participants was estimated using inverse probability-of-treatment-and-censoring (IPTC)-weighted estimation of a marginal...
- HAART may reduce non-HIV/AIDS-related comorbidities in patients with HIV. // Hem/Onc Today;11/25/2008, Vol. 9 Issue 21, p70
The article discusses research being done on the link of highly-active antiretroviral therapy (HAART) with reduced comorbidities not related to human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) in patients with cluster of differentiation (CD4) cell counts less than 350...
- Increase in CD4 cell counts between 2 and 3.5 years after initiation of antiretroviral therapy and determinants of CD4 progression in India. Rajasekaran, S.; Jeyaseelan, L.; Raja, K.; Vijila, S.; Krithigaipriya, K. A.; Kuralmozhi, R. // Journal of Postgraduate Medicine;Oct2009, Vol. 55 Issue 4, p261
Background: Estimation of CD4 cell count remains the primary monitoring tool in assessing efficacy or failure of Anti Retroviral Therapy (ART) under national program conditions in India. Aims: To study the average trajectory of CD4 cell count after two years of initiation of potent ART and to...
- Low-level HIV-1 replication and the dynamics of the resting CD4+ T cell reservoir for HIV-1 in the setting of HAART. Sedaghat, Ahmad R.; Siliciano, Robert F.; Wilke, Claus O. // BMC Infectious Diseases;2008, Vol. 8 Issue 1, Special section p1
Background: In the setting of highly active antiretroviral therapy (HAART), plasma levels of human immunodeficiency type-1 (HIV-1) rapidly decay to below the limit of detection of standard clinical assays. However, reactivation of remaining latently infected memory CD4+ T cells is a source of...
