Relapsing hypocupraemic myelopathy requiring high-dose oral copper replacement

Prodan, C. I.; Bottomley, S. S.; Holland, N. R.; Lind, S. E.
September 2006
Journal of Neurology, Neurosurgery & Psychiatry;Sep2006, Vol. 77 Issue 9, p1092
Academic Journal
Adult-onset copper deficiency with neurological manifestations is a newly recognised syndrome. Long-term oral copper replacement therapy has been the mainstay of treatment in the literature. A case of relapsing hypocupraemic myelopathy responsive to increased doses of copper replacement is reported. Standard doses of copper may not be sufficient for all patients.


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