Wheezing, asthma, hay fever, and atopic eczema in relation to maternal occupations in pregnancy

Magnusson, L. L.; Wennborg, H.; Bonde, J. P.; Olsen, J.
September 2006
Occupational & Environmental Medicine;Sep2006, Vol. 63 Issue 9, p640
Academic Journal
Objectives: To examine whether prenatal occupational exposures, especially to organic solvents, are associated with atopic diseases in childhood. Methods: The study comprised children born in Odense or Aalborg, Denmark between 1984 and 1987. Occupational job titles were derived from questionnaires filled out by the mothers when attending midwife centres. Assessment of organic solvent exposures was based on job titles selected by occupational specialists. A follow up questionnaire to the parents provided data on medical diagnoses as well as wheezing symptoms for 7844 children aged 14–18. Multivariate logistic regression analyses were performed to estimate the cumulative risk for wheezing (early wheezing not diagnosed as asthma), asthma, hay fever, and atopic eczema during childhood by means of odds ratios (OR) and 95% confidence intervals (CI). Results: Explorative analyses by maternal job titles in pregnancy showed elevated odds ratios concerning different atopic diseases for occupational groups such as ‘bakers, pastry cooks, and confectionary makers’, ‘dental assistants’, ‘electrical and electronic assemblers’, ‘sewers and embroiders’, and ‘bookbinders and related workers’. An excess risk ratio for hay fever (OR 2.8, CI 1 .1 to 7.5) was found following maternal gestational exposure to organic solvents. Furthermore, a slightly raised odds ratio for asthma was observed in children of shift workers (OR 1 .2, CI 1 .0 to 1 .5). Conclusion: The data suggest links between certain maternal occupations during pregnancy and atopic diseases, which merits further scrutiny. However, no consistent pattern was seen across the different atopic diseases.


Related Articles

  • Mothers' blow to hygiene theory.  // New Scientist;7/24/2004, Vol. 183 Issue 2457, p18 

    Women have a weaker immune response to allergens with each successive pregnancy, which might explain why children born later tend to suffer less from eczema, hay fever and asthma than their older siblings. Wilfried Karmaus at Michigan State University in East Lansing and his colleagues had...

  • Antibiotic Use and Symptoms of Asthma, Allergic Rhinitis and Eczema in Children. Karimi, Mehran; Mirzaei, Mohsen // Iranian Journal of Pediatrics;Jun2009, Vol. 19 Issue 2, p141 

    Objective: Allergic diseases are frequent in children and their prevalence and severity differ in different regions of the world. It has been hypothesized that antibiotic use, early in life, may increase the subsequent risk of asthma and other allergic disorders. The aim of this study was to...

  • Atopic eczema in children: Diagnosis and management.  // British Journal of School Nursing;Mar2010, Vol. 5 Issue 2, p69 

    The article discusses the causes and management of atopic eczema (AE) in children in Great Britain. It states that the cause of AE is unknown but there is a family history of the condition which is associated with the problems of asthma and hay fever. It mentions that school nurses come in...

  • Farmers' Children May Be Protected From Asthma, Hay Fever, and Eczema. Theuvenin, Frederique H. // Pulmonary Reviews;Oct2008, Vol. 13 Issue 10, p15 

    The article discusses research being done on the role of farm exposure in utero in the prevention of asthma, hay fever and eczema. It references a study by Jeroen Douwes et al, published in the September 2008 issue of "European Respiratory Journal." The study shows that asthma, hay fever and...

  • A Meta-Analysis of the Association Between Childhood Type 1 Diabetes and Atopic Disease. Cardwell, Chris R.; Shields, Mike D.; Carson, Dennis J.; Patterson, Chris C. // Diabetes Care;Sep2003, Vol. 26 Issue 9, p2568 

    OBJECTIVE — To review the published literature and perform a meta-analysis summarizing the evidence in support of an inverse association between type 1 diabetes and the atopic disorders: asthma, eczema, and allergic rhinitis in children. RESEARCH DESIGN AND METHODS — MEDLINE, Web...

  • Allergy and sibship size association goes back years.  // Nursing Standard;3/22/2006, Vol. 20 Issue 28, p19 

    The article examines the association between sibship size and allergic disease in individuals born between 1918 and 1952. From 14,140 men and women, 1,677 have a positive history of one the three allergic diseases. These include asthma, eczema-urticaria and hay fever. It was found that the...

  • Hay fever and perennial allergic rhinitis. Bostock-Cox, Bev // Practice Nurse;3/12/2010, Vol. 39 Issue 5, p11 

    The article provides health information on the diagnosis and management of hay fever and perennial allergic trinities. Asthma and eczema are allergic disorders that may also cause allergic rhinitis. Diagnostic procedures include the identification of personal or family history of hay fever or...

  • Maternal age of menarche is not associated with asthma or atopy in prepubertal children. Maitra, A.; Sherriff, A.; Northstone, K.; Strachan, D.; Henderson, A. J.; ALSPAC Study Team // Thorax;Oct2005, Vol. 60 Issue 10, p810 

    Background: Maternal sex hormones in pregnancy can theoretically influence the developing fetal immune system and modulate the subsequent development of atopic disorders. Early onset of menarche has been linked to increased oestrogen levels in adult women. A study was undertaken to...

  • Can paracetamol use in pregnancy cause child asthma? Rosenthal, Mark // Pulse;3/1/2004, Vol. 64 Issue 9, p76 

    Presents a question and answer advisory on the relation of paracetamol use during pregnancy to child asthma. Occurrence of wheezing sounds in children aged three; Overall prevalence of wheezing; Consideration of the frequency of paracetamol use.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics