RECENT ADVANCES IN CLINICAL PRACTICE VALUE OF GENETIC TESTING IN THE MANAGEMENT OF PANCREATITIS
- TCF7L2 gene polymorphisms do not predict susceptibility to diabetes in tropical calcific pancreatitis but may interact with SPINK1 and CTSB mutations in predicting diabetes. Mahurkar, Swapna; Bhaskar, Seema; Reddy, D. Nageshwar; Prakash, Swami; Rao, G. Venkat; Singh, Shivaram Prasad; Thomas, Varghese; Chandak, Giriraj Ratan // BMC Medical Genetics;2008, Vol. 9, Special section p1
Background: Tropical calcific pancreatitis (TCP) is a type of chronic pancreatitis unique to developing countries in tropical regions and one of its important features is invariable progression to diabetes, a condition called fibro-calculous pancreatic diabetes (FCPD), but the nature of diabetes...
- Update on the approaches to pancreatic disease. Abbruzzese, James L.; Lowy, Andrew M.; Pleskow, Douglas; Xiong, Henry Q. // Patient Care;Feb2006, Vol. 40 Issue 2, p15
Presents an update on the approaches to pancreatic disease. Diagnosis; Causes; Signs and symptoms.
- Predicting the Prognosis of Acute Pancreatitis. Forsmark, Chris E.; Yadav, Dhiraj // Annals of Internal Medicine;10/4/2016, Vol. 165 Issue 7, p523
The author reflects on the stratification that allow clinicians to triage patient and identify the appropriate therapy, prognosis, course of disease and duration of hospitalization in individual patients. Topics discussed includes Acute pancreatitis (AP), gastrointestinal condition in patient...
- Differential diagnosis between chronic pancreatitis and pancreatic cancer: value of the detection of KRAS2 mutations in circulating DNA. Maire, F.; Micard, S.; Hammel, P.; Voitot, H.; Levy, P.; Cugnenc, P.-H.; Ruszniewski, P.; Puig, P. Laurent // British Journal of Cancer;8/27/2002, Vol. 87 Issue 5, p551
KRAS2 mutations in codon 12 have been detected in about 80% of pancreatic cancers. The aim of this study was to evaluate the value of KRAS2 mutations detection in circulating deoxyribo nucleic acid to differentiate pancreatic cancer from chronic pancreatitis. Circulating deoxyribo nucleic acid...
- Genomic Diversities and Affinities among Four Endogamous Groups of Punjab (India) Based on Autosomal and Mitochondrial DNA Polymorphisms. Kaur, Inderjeet; Roy, Sangita; Chakrabarti, Subharbrata; Sarhadi, Virinder Kaur; Majumber, Partha P.; Bhanwer, A.J.S.; Singh, Jai Rup // Human Biology;Dec2002, Vol. 74 Issue 6, p819
Nineteen insertion/deletion and restriction site polymorphisms on autosomal and mitochondrial genomes and mitochondrial DNA hypervariable segment 1 sequences were used to study genetic diversities and affinities among four endogamous groups of Punjab, India. High values of heterozygosity were...
- Strangulation of the Colon Complicating Acute Pancreatitis. Tenner, Scott; Silverman, Stuart G.; Brooks, David; Banks, Peter A. // American Journal of Gastroenterology;Sep1995, Vol. 90 Issue 9, p1511
We report a patient with alcohol-induced necrotizing pancreatitis who developed a severe ileus followed by incarceration of a portion of the transverse colon within a ventral hernia. Laparotomy 9 days after the onset of symptoms revealed infarction of the transverse colon and infection of the...
- Multiple Anomalies of Pancreaticobiliary Ductal System: Report of a Case. Chun-Hsiang Wang; Lein-Ray Mo // American Journal of Gastroenterology;Oct1999, Vol. 94 Issue 10, p3086
Describes the case of a patient with multiple anomalies of pancreaticobiliary ductal system. Medical history of the patient; Symptoms presented; Result of the patient's pancreatogram.
- Pancreatic TB: Diagnosis by Needle Aspiration. Koduri, Venu G.; Janardhanan, Ravi; Hagan Jr., Paul; Brodmerkel Jr., George J. // American Journal of Gastroenterology;Sep1992, Vol. 87 Issue 9, p1206
Presents the case of pancreatic tuberculosis diagnosed by the fine-needle aspiration technique. Medical history of the patient; Incidence rate of pancreatic tuberculosis; Diagnostic procedures for pancreatic mass evaluation.
- EDITORIAL COMMENT. Greenstein, Adrian J. // American Journal of Gastroenterology;Feb1974, Vol. 61 Issue 2, p151
Advocates the need to consider clinical signs in the study of diseases. Factors which led to the disregard for clinical signs; Implication of isotopic and biochemical methods in studying diseases for the development of clinical signs as a skilled art; Significance of recognizing clinical signs...