Probiotics for Crohn's disease: what have we learned?

Prantera, C.
June 2006
Gut;Jun2006, Vol. 55 Issue 6, p757
Academic Journal
The article analyzes the therapeutic use of probiotics for patients afflicted with Crohn's disease, either in the acute phase or for maintenance. It was observed that the intestinal flora is the essential factor in triggering the Crohn's inflammatory process in genetically prone patients. Thus immunosuppressors are used to reduce the host response and antibiotics are used to suppress the bacterial flora, with a consequent decreased activation of the gut immune system. It is suggested that theoretically it would be better to remove the harmful cause instead of curtailing the host defenses by inducing a form of immunodeficiency that is prone to opportunistic infections.


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