TITLE

TRANSFUSION TRANSMITTED LEISHMANIASIS: A CASE REPORT AND REVIEW OF LITERATURE

AUTHOR(S)
Dey, A.; Singh, S.
PUB. DATE
July 2006
SOURCE
Indian Journal of Medical Microbiology;Jul2006, Vol. 24 Issue 3, p165
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Leishmaniasis is caused by the infection of haemoparasite Leishmania. The disease is a major public health problem in at least 88 countries, including India. Various species of Leishmania are involved in causing this disease. In India, Leishmania donovani species causes visceral leishmaniasis or kala-azar. The parasite is mainly transmitted from infected to uninfected person through the bites of female sandfly. Rarely the parasite can transmit through placenta from mother to child, through sexual intercourse, as laboratory acquired and through blood transfusion. This paper reports a unique case of transfusion-transmitted fatal kala-azar in an Indian infant who acquired this infection within few days of his birth after receiving blood from his maternal uncle, who was asymptomatic at the time of blood donation but died due to severe kala-azar within three months. The baby started having fever and developed hepatosplenomegaly within one month of blood transfusion and in spite of repeated anti-leishmanial treatment with sodium antimony gluconate the child died at the age of 7 months. This paper details the clinico-pathological findings of this child and also reviews the literature on this aspect and its impact on transfusion medicine.
ACCESSION #
22150593

 

Related Articles

  • WHO action in Afghanistan aims to control debilitating leishmaniasis.  // Weekly Epidemiological Record;8/27/2004, Vol. 79 Issue 35, p319 

    The article presents information on the actions taken by World Health Organization (WHO) in Afghanistan to control debilitating Leishmaniasis. Kabul is the largest centre of cutaneous leishmaniasis in the world, with an estimated 67 500 cases. To avert a sharp increase in the number of cases,...

  • Short-Course Paromomycin Treatment of Visceral Leishmaniasis in India: 14-Day vs 21-Day Treatment. Sundar, Shyam; Agrawal, Neha; Arora, Rakesh; Agarwal, Dipti; Rai, Madhukar; Chakravarty, Jaya // Clinical Infectious Diseases;9/15/2009, Vol. 49 Issue 6, p914 

    Background. Treatment of visceral leishmaniasis (VL) is far from satisfactory. There is an urgent need for a therapy that is efficacious, safe, affordable, and of short duration. Methods. A randomized open-label study was conducted to assess the efficacy and safety of 2 regimens of paromomycin...

  • Avalia��o do Sistema de Vigil�ncia Sanit�ria do Sangue em �mbito federal, Brasil, 2007. Mota, Daniel Marques; Coradi Freitas, Daniel Roberto; De Ara�jo, Wildo Navegantes // Revista Ci�ncia & Sa�de Coletiva;2012, Vol. 17 Issue 1, p191 

    This study evaluated the Sanitary Vigilance System for Blood at federal government level (VIGISAN). This assessment included the following components: managerial system of registration of hemotherapeutic services; external evaluation program of quality of hemotherapy services; hemovigilance...

  • Cutaneous Leishmaniasis in U.S. Military Personnel--Southwest/Central Asia, 2002-2003.  // MMWR: Morbidity & Mortality Weekly Report;10/24/2003, Vol. 52 Issue 42, p1009 

    Provides preliminary data about cases of cutaneous leishmaniasis (CL) in military personnel deployed during 2002-2003 to Afghanistan, Iraq and Kuwait. Treatment given to the patient; Estimate made by the World Health Organization on cases of CL and of visceral leishmaniasis that occur each...

  • Leishmaniasis in Organ Transplant Recipients. Deresinski, Stan // Clinical Infectious Diseases;3/15/2006, Vol. 42 Issue 6, preceding p739 

    This article cites a research study focusing on the cases of Leishmaniasis in the recipients of organ transplant. Eleven new cases of visceral leishmaniasis in recipients of organ transplants were reported in Southern France. Visceral leishmaniasis is an important problem in some areas of...

  • INFECÇÕES PARASITÁRIAS TRANSMITIDAS POR TRANSFUSÃO DE SANGUE. PEREIRA, Branca Isabel; NAZARETH, Cláudia; MALCATA, Lurdes; ALVES, Helena; FERNÁNDEZ, José Rafael; Sargento, Celene; CUNHA, Saraiva da // Acta Medica Portuguesa;SUP2011, Vol. 24 Issue S4, p897 

    Protozoal infections that are efficiently transmitted by blood transfusion include Malaria, Chagas Disease, African Trypanosomiasis, Leshmaniasis, Toxoplasmosis and Babesiosis. With exception of Toxoplasmosis and Leishmaniasis, these diseases are endemic in mainly tropical low income countries...

  • Febrile Nonhemolytic Transfusion Reactions. Ezidiegwu, Christian N.; Lauenstein, Karla J.; Rosales, Lazaro G.; Kelly, Karen C.; Henry, John Bernard // Archives of Pathology & Laboratory Medicine;Sep2004, Vol. 128 Issue 9, p991 

    Context-Febrile nonhemolytic transfusion reactions (FNHTRs) cause unwelcome interruptions during the course of blood product transfusions and necessitate measures to verify the nature of the reaction and to exclude certain dangerous reactions, such as hemolytic and septic phenomena....

  • Thermotherapy. An alternative for the treatment of American cutaneous leishmaniasis. L¢pez, Liliana; Robayo, Martha; Vargas, Margarita; V‚lez, Iv n D. // Trials;2012, Vol. 13 Issue 1, p58 

    Background: Pentavalent antimonials (Sb5) and miltefosine are the first-line drugs for treating cutaneous leishmaniasis in Colombia; however, toxicity and treatment duration negatively impact compliance and cost, justifying an active search for better therapeutic options. We compared the...

  • DISTRIBUCION DE VECTORES DE LEISHMANIASIS VISCERAL EN LA PROVINCIA DE CORRIENTES, 2008. Salomon, Oscar Daniel; Ramos, Ladys K.; Quintana, Maria Gabriela; Acardi, Soraya A.; Santini, Maria Soledad; Schneider, Adolfo // Medicina (Buenos Aires);2009, Vol. 69 Issue 6, p625 

    Visceral leishmaniasis (VL) is a relevant parasitic disease in public health, produced by Leishmania infantum chagasi. Since the urbanization and emergence in Southern Brazil and Paraguay, the vector Lutzomyia longipalpis in Formosa, 2004, and the first human visceral leishmaniasis case in...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics