Autoimmune pancreatitis associated with renal lesions mimicking metastatic tumours

Rudmik, Lucas; Trpkov, Kiril; Nash, Carla; Kinnear, Susan; Falck, Vincent; Dushinski, John; Dixon, Elijah
August 2005
CMAJ: Canadian Medical Association Journal;8/15/2006, Vol. 175 Issue 4, p367
Academic Journal
Autoimmune pancreatitis is a chronic inflammatory disorder that is often misdiagnosed as pancreatic cancer. Since autoimmune pancreatitis is benign and responds to steroid management, it is important to diagnose it to avoid unnecessary surgical intervention. We describe a novel case of IgG4-associated autoimmune pancreatitis presenting with tubulointerstitial nephritis as renal lesions mimicking metastatic tumours but with no change in renal function.


Related Articles

  • Cystic Lesions in Autoimmune Pancreatitis. Gompertz, Macarena; Morales, Claudia; Aldana, Hernán; Castillo, Jaime; Berger, Zoltán // Case Reports in Gastroenterology;Sep-Dec2015, Vol. 9 Issue 3, p366 

    Autoimmune pancreatitis (AIP) can be chronic or recurrent, but frequently completely reversible after steroid treatment. A cystic lesion in AIP is a rare finding, and it can mimic a pancreatic cystic neoplasm. Difficulties in an exact diagnosis interfere with treatment, and surgery cannot be...

  • Renal lesions associated with autoimmune pancreatitis: CT findings. Triantopoulou, Charikleia; Malachias, George; Maniatis, Petros; Anastopoulos, John; Siafas, Ioannis; Papailiou, John // Acta Radiologica;Jul2010, Vol. 51 Issue 6, p702 

    Background: Autoimmune pancreatitis (AIP) is a chronic inflammatory condition characterized by IgG4-positive plasma cells. Recent evidence suggests that it is a systemic disease affecting various organs. Tubulointerstitial nephritis has been reported in association with AIP. Purpose: To...

  • nephritis.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1554 

    An encyclopedia entry for "nephritis" is presented. The term refers to the inflammation of the kidneys, which can either be acute or chronic. Possible causes of the medical condition are bacteria or their toxins, autoimmune disorders or toxic chemicals. It also offers information on patient...

  • Experimental induction of salt-sensitive hypertension is associated with lymphocyte proliferative response to HSP70. Parra, Gustavo; Quiroz, Yasmir; Salazar, Jenny; Bravo, Yanauri; Pons, Hector; Chavez, Maribel; Johnson, Richard J.; Rodriguez-Iturbe, Bernardo // Kidney International Supplement;Dec2008, Issue 111, pS55 

    Renal tubulointerstitial inflammation is a constant feature of experimental models of hypertension and likely plays a role in the pathogenesis of salt-sensitive hypertension. We have previously raised the possibility that the immune cell infiltration is driven by a low grade autoimmune...

  • Are Dysregulated Inflammatory Responses to Commensal Bacteria Involved in the Pathogenesis of Hepatobiliary-Pancreatic Autoimmune Disease? An Analysis Using Mice Models of Primary Biliary Cirrhosis and Autoimmune Pancreatitis. Yanagisawa, Naoko; Haruta, Ikuko; Kikuchi, Ken; Shibata, Noriyuki; Yagi, Junji // ISRN Gastroenterology;2011, Special section p1 

    The etiopathogenesis of many autoimmune disorders has not been identified. The aim of this paper is to focus on the involvement of bacterial exposure in the pathogenesis of primary biliary cirrhosis (PBC) and autoimmune pancreatitis (AIP), both of which are broadly categorized as autoimmune...

  • Is it time to reconsider autoimmune pancreatitis? Kamisawa, Terumi // Journal of Gastroenterology;Dec2006, Vol. 41 Issue 12, p1240 

    The author reflects on the study about autoimmune pancreatitis (AIP). The characteristic features of AIP including its association with various extrapancreatic lesions are mentioned, as well the five major extrapancreatic lesions. The author agrees with the proposed systemic entity of...

  • Prevalence and distribution of extrapancreatic lesions complicating autoimmune pancreatitis. Hamano, Hideaki; Arakura, Norikazu; Muraki, Takashi; Ozaki, Yayoi; Kiyosawa, Kendo; Kawa, Shigeyuki // Journal of Gastroenterology;Dec2006, Vol. 41 Issue 12, p1197 

    Autoimmune pancreatitis is a unique form of chronic pancreatitis characterized by high serum IgG4 concentrations and abundant IgG4-bearing plasma cell infiltration in the pancreatic lesion, and it has been reported to be associated with a variety of extrapancreatic lesions, leading us to...

  • Autoimmune Pancreatitis: Pathologic Subtypes and Their Implications for Its Diagnosis. Sugumar, Aravind; Klöppel, Günter; Chari, Suresh T. // American Journal of Gastroenterology;Sep2009, Vol. 104 Issue 9, p2308 

    Autoimmune pancreatitis (AIP) is a rare but treatable form of pancreatic disease that is being increasingly recognized worldwide. The diagnosis of AIP remains a clinical challenge and the difficulty is compounded by the fact that there are no internationally agreed on diagnostic criteria for...

  • Autoimmune pancreatitis as the initial presentation of systemic lupus erythematosus. Kobayashi, S.; Yoshida, M.; Kitahara, T.; Abe, Y.; Tsuchida, A.; Nojima, Y. // Lupus;2007, Vol. 16 Issue 2, p133 

    Pancreatitis is a relatively rare complication in systemic lupus erythematosus (SLE). Here we present a case of SLE associated with autoimmune pancreatitis. A 37-year old woman was admitted to our hospital because of fever, skin rash, proteinuria and abdominal pain. A diagnosis of SLE was made...


Read the Article


Sign out of this library

Other Topics