TITLE

Is there another way to take account of noncompliance in randomized controlled trials?

AUTHOR(S)
Hewitt, Catherine E.; Torgerson, David J.; Miles, Jeremy N. V.
PUB. DATE
August 2005
SOURCE
CMAJ: Canadian Medical Association Journal;8/15/2006, Vol. 175 Issue 4, p347
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on alternative ways of taking account of noncompliance in the design and conduct of randomized controlled trials (RCT). It has been recommended that the primary analysis of an RCT should utilize intention to treat (ITT). An alternative to the ITT approach is the complier average causal effect, which is also known as the local average treatment effect. A chart is presented which compared rate of death from colorectal cancer among those who attended or did not attend medical screening.
ACCESSION #
21988385

 

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