Heart valve structure: a predisposing factor for rheumatic heart disease

Nayar, S.; Nayar, P. G.; Cherian, K. M.
August 2006
Heart;Aug2006, Vol. 92 Issue 8, p1151
Academic Journal
The study examines the mitral and aortic valves surgically removed due to stenosis or regurgitation or from double valve replacements and determines the hyaluronic acid content of the valves to determine the predisposing factors for rheumatic heart disease. An increase in myxomatous tissue was observed in 47%, 58%, and 67% of the mitral, tricuspid aortic, and bicuspid aortic valves, respectively. Microscopic examination revealed commissural fusion, neovascularization, and mononuclear cell collection in the valves examined suggesting infection.


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