TITLE

Is Crohn's due to sick phagocytes?

PUB. DATE
August 2006
SOURCE
Gut;Aug2006, Vol. 55 Issue 8, p1197
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses the role of phagocytes in causing Crohn's disease. Researchers have found that diseases affecting neutrophil function, such as chronic granulomatous disease and glycogen storage disease cause Crohn's disease. Researchers from London, England, have shown that impaired accumulation of neutrophils and reduced interleukin 8 production in response to gut trauma was a normal symptom. Reduced responses in the gut wall to bacteria was the primary defect in Crohn's.
ACCESSION #
21843693

 

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