How do SSRIs help patients with irritable bowel syndrome?

Creed, F.
August 2006
Gut;Aug2006, Vol. 55 Issue 8, p1065
Academic Journal
The article discusses the use of selective serotonin reuptake inhibitor (SSRI) for the treatment of depression patients with irritable bowel syndrome (IBS). In case of non-depressed IBS patients, placebo was found to be better than fluoxetine for improving the condition of patients. SSRI antidepressants did improve the well-being in some patients with IBS by improving their abdominal pain and bowel symptoms, but didn't show any improvement in their depression.


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