Scientific support for off-label prescriptions absent in 73% of cases

July 2006
Formulary;Jul2006, Vol. 41 Issue 7, p336
Academic Journal
The article discusses a study published in the "Archives of Internal Medicine" which suggest that 73% of the off-label medication prescriptions the authors researched had little or no scientific support. Researchers defined the prescribing patterns by diagnosis for 160 commonly prescribed drugs in what they claimed was the first study to systematically characterize the extent of off-label prescribing in general outpatient care. They found that off-label use was most common among cardiac medications and anticonvulsants.


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