Review: The Wells clinical prediction guide and D-dimer testing predict deep venous thrombosis

July 2006
ACP Journal Club;Jul/Aug2006, Vol. 145 Issue 1, p24
Academic Journal
The article presents information on a study related to the prediction of deep venous thrombosis (DVT) in patients. It discusses the validity of Wells clinical prediction guide to assess the clinical probability of various types of DVT before D-dimer testing or diagnostic imaging. An analysis of the result reveals that specificity of D-dimer testing is reduced as the clinical probability escalates from low to high sensitivity assays. Thus, it is concluded that low clinical probability on the guide along with negative D-dimer test results excludes the presence of DVT in patients.


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