Glucosamine and chondroitin sulfate did not improve pain in osteoarthritis of the knee: COMMENTARY

Baime, Michael J.
July 2006
ACP Journal Club;Jul/Aug2006, Vol. 145 Issue 1, p17
Academic Journal
The article presents the author's comments on how chondroitin sulfate and glucosamine are popular nutritional supplements and how they slow the progression of osteoarthritis. According to the author, many researchers have learned that the positive effects of treatment are unlikely to be clinically important for most patients. The author further states that the response to placebo was a surprisingly high 60%, which could have diluted a true treatment effect and after twenty four weeks of treatment, there was no statistically difference among groups for the primary endpoint.


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