Maintenance treatment with paroxetine, but not psychotherapy, prevented recurrent major depression in older persons: COMMENTARY

Williams Jr., John W.
July 2006
ACP Journal Club;Jul/Aug2006, Vol. 145 Issue 1, p13
Academic Journal
The article presents information on a study which determines that major depression is less common in older adults than in those who are middle-aged. The study findings suggest that a meta-analysis of thirty one randomized discontinuation trials in mixed-aged populations show that maintenance antidepressant medication decreases twelve month relapse rates from 41% to 18%. In the study, researchers finds that further researchers of combined antidepressant medication and psychotherapy are needed to determine the role of psychotherapies in relapse prevention in older adults.


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