Calcium plus vitamin D did not prevent hip fracture or colorectal cancer in postmenopausal women: COMMENTARY

Fletcher, Robert H.
July 2006
ACP Journal Club;Jul/Aug2006, Vol. 145 Issue 1, p5
Academic Journal
The article presents the author's views about two reports from the Women's Health Initiative randomized controlled trials. The reports do not favors the generally held belief that calcium plus vitamin D supplementation prevents colorectal cancer and fractures. The trial for colorectal cancer prevention was not a strong test of the assumption that calcium plus vitamin D supplementation act as protective over the long term. In another report regarding fractures, the results were not so much important, they only suggested a small protective outcome.


Related Articles

  • Government Gets it Wrong Again: US Recommendation for Vitamin D and Calcium Supplementation is Too Low. Grant, William B. // Townsend Letter;Jan2013, Issue 354, p22 

    The article critiques the U.S. recommendation for vitamin D and calcium supplementation. It references the report "Vitamin D and calcium supplementation to prevent cancer and osteoporotic fractures in adults: U.S. Preventive Services Task Force Recommendation Statement" published online on June...

  • Calcium supplementation, with or without vitamin D, prevents osteoporotic fractures in people >= 50 years of age. Jamal, Sophie A; Emanoilidis, Helen // ACP Journal Club;Mar/Apr2008, Vol. 148 Issue 2, p15 

    The article focuses on randomized controlled trials (RCTs) investigating if calcium supplementation, with or without vitamin D, prevents osteoporotic fractures in 50 year old patients. Trials found out that calcium supplementation, with or without vitamin D, prevents osteoporotic fractures and...

  • Resolving Vitamin D Deficiency in the Preconception Period among High-Risk Reproductive Women: A Randomized Controlled Trial. Taheri, Mahshid; Baheiraei, Azam; Foroushani, Abbas Rahimi; Modarres, Maryam // Iranian Red Crescent Medical Journal;Jan2014, Vol. 16 Issue 1, p1 

    Background: Although vitamin D deficiency has been linked to potential complications in reproductive women, the recommended intake dosage of this vitamin in populations with high incidence of deficiency in preconception period has not been defined. Objectives: The study investigated the effect...

  • Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers. Lippman, Scott M.; Klein, Eric A.; Goodman, Phyllis J.; Lucia, M. Scott; Thompson, Ian M.; Ford, Leslie G.; Parnes, Howard L.; Minasian, Lori M.; Gaziano, J. Michael; Hartline, Jo Ann; Parsons, J. Kellogg; Bearden III, James D.; Crawford, E. David; Goodman, Gary E.; Claudio, Jaime; Winquist, Eric; Cook, Elise D.; Karp, Daniel D.; Walther, Philip; Lieber, Michael M. // JAMA: Journal of the American Medical Association;1/7/2009, Vol. 301 Issue 1, p39 

    The article presents a randomized controlled trial which examined whether selenium, vitamin E, or both could prevent prostate cancer and other diseases with little or no toxicity in healthy men. Participants were African American men 50 years or older and non-African American men 55 years or...

  • Fighting--or feeding--colon cancer.  // Consumer Reports on Health;Aug2003, Vol. 15 Issue 8, p10 

    Reports on the prevention of colon cancer through intake of calcium and vitamin D. Reduction in the risk of developing cancer with increased calcium intake from food; Effect of vitamin D in strengthening bones.

  • Vitamin D and calcium is effective in preventing fractures but vitamin D alone is not.  // Australian Journal of Pharmacy;Aug2010, Vol. 91 Issue 1083, p86 

    The article discusses the effects of vitamin D supplementation without calcium in the incidence of fractures. It highlights the findings of randomised controlled trials which revealed no significant effects of vitamin D supplementation without calcium. It states that vitamin D must be taken with...

  • Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial. Yuelong Cao; Jones, Graeme; Cicuttini, Flavia; Winzenberg, Tania; Wluka, Anita; Sharman, James; Kay Nguo; Changhai Ding // Trials;2012, Vol. 13 Issue 1, p131 

    Background: Osteoarthritis (OA) is a common health issue worldwide in the aging population who are also commonly deficient in vitamin D. Our previous study suggested that higher serum 25-(OH)D levels were associated with reduced knee cartilage loss, implying that vitamin D supplementation may...

  • Chemoprevention of colorectal cancer in Japan: a brief introduction to current clinical trials. Ishikawa, Hideki; Nakamura, Tomiyo; Kawano, Atsuko; Gondo, Nobuhisa; Sakai, Toshiyuki // Journal of Gastroenterology;2009 Supplement 19, Vol. 44, p77 

    The rapidly increasing incidence of colorectal cancer in Japan poses a great challenge to researchers to develop preventive strategies against this disease. Thus far, several clinical trials for this purpose have been planned in Japanese subjects; some have been completed and documented while...

  • Calcium plus vitamin D did not prevent hip fracture or colorectal cancer in postmenopausal women.  // ACP Journal Club;Jul/Aug2006, Vol. 145 Issue 1, p4 

    The article presents a study according to which in postmenopausal women, calcium plus vitamin D does not prevent colorectal cancer or hip fracture. The study was conducted at 40 medical centers in the U.S. on 36282 healthy postmenopausal women. The age of the women ranged from 50 to 79 years....


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics