Lowering homocysteine with folic acid and B vitamins did not prevent vascular events in vascular disease: COMMENTARY

Shekelle, Paul
July 2006
ACP Journal Club;Jul/Aug2006, Vol. 145 Issue 1, p2
Academic Journal
The article presents the author's views regarding the dramatic effect of simple and cheap pills in cardiovascular diseases (CV). The first trial was performed on 3680 patients in which a high-dose combination of B vitamins and folate with a control pill of low doses were given to the patients. The speculation was that taking the pill will decrease the plasma levels of homocysteine and will help to reduce the CV events. In spite of an increase in blood levels of folate and B vitamins their was no effect on stroke in the patients.


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