Lowering homocysteine with folic acid and B vitamins did not prevent vascular events in vascular disease

July 2006
ACP Journal Club;Jul/Aug2006, Vol. 145 Issue 1, p2
Academic Journal
The article presents a study which states that lowering homocysteine along with B vitamins and folic acid did not interrupt vascular events in patients with vascular diseases. The study included 5522 patients with age above 55 years. All the patients had a history of peripheral artery diseases. Of the total patients, 9% had a history of stroke and other 54% had a history of myocardial infarction. Patients were selected for the regardless of homocysteine levels.


Related Articles

  • Lowering homocysteine with folic acid and B vitamins did not prevent vascular events after myocardial infarction.  // ACP Journal Club;Jul/Aug2006, Vol. 145 Issue 1, p3 

    The article presents a study which states that lowering homocysteine with B vitamins and along with folic acid did not interrupt vascular events in patients with myocardial infarction (MI). The study included 3749 patients with age ranged from 30 to 85 years and had acute MI in the last 7 days....

  • Should we prescribe folic acid in MI?  // Pulse;1/12/2004, Vol. 64 Issue 2, p64 

    Discusses whether myocardial infarction (MI) patients be prescribed folic acid supplements. Reasons why folic acid is thought to be of benefit to MI patients; Characteristics of MI; Administration of folic acid.

  • Homocysteine Trials – Clear Outcomes for Complex Reasons. Loscalzo, Joseph // New England Journal of Medicine;4/13/2006, Vol. 354 Issue 15, p1629 

    The article focuses on a study that was conducted to determine the consequences on cardiovascular events of lowering serum homocysteine concentrations with the use of folic acid, vitamin B12, and vitamin B6. The vitamin treatment was associated with reduction in plasma homocysteine concentration...

  • The Cover.  // JAMA: Journal of the American Medical Association;4/7/2015, Vol. 313 Issue 13, preceding p1291 

    The table of contents for the April 7, 2015 issue of "Journal of the American Medical Association" (JAMA) is presented.

  • Methoxistasis: Integrating the Roles of Homocysteine and Folic Acid in Cardiovascular Pathobiology. Joseph, Jacob; Loscalzo, Joseph // Nutrients;Aug2013, Vol. 5 Issue 8, p3235 

    Over the last four decades, abnormalities in the methionine-homocysteine cycle and associated folate metabolism have garnered great interest due to the reported link between hyperhomocysteinemia and human pathology, especially atherothrombotic cardiovascular disease. However, clinical trials of...

  • B-lieve it. Snyder, Karyn // Drug Topics;9/15/97, Vol. 141 Issue 18, p53 

    Focuses on researches which indicate that a diet low in animal protein and high in vitamin B is essential in heart attack prevention. Information on the believe that vitamins B6, B12 and folic acid may counter homocysteine's damaging effect on arteries; Reference to a profile of Kilmer McCully...

  • Role of homocysteine & MTHFR C677T gene polymorphism as risk factors for coronary artery disease in young Indians. Gupta, Santosh Kumar; Kotwal, Jyoti; Kotwal, Atul; Dhall, Anil; Garg, Salil // Indian Journal of Medical Research;Apr2012, Vol. 135 Issue 4, p506 

    Background & objectives: Hyperhomocysteinaemia (HCA) either due to mutation of MTHFR gene or deficiency of vitamin B12 and folic acid, has been reported as a risk factor for coronary artery disease (CAD). The present study was aimed to determine plasma homocysteine (Hcy) levels and to evaluate...

  • New benefits for brain & heart. Solan, Matthew // Natural Health;Feb2006, Vol. 36 Issue 2, p99 

    This article reports that recent investigations have given scientists a better idea of how valuable folate can be. A study at Wageningen University in the Netherlands found that taking 800 mcg folic acid every day helped preserve brain function. A report in the Archives of General Psychiatry...

  • Influence of serum folic acid levels on plasma homocysteine concentrations in patients with rheumatoid arthritis. Tiftikci, Arzu; Ozdemir, Ali; Tarcin, Ozlem; Tarcin, Orhan; Inanc, Nevsun; Sahinoglu, Sureyya; Direskeneli, Haner; Yavuz, Sule; Uras, Fikriye; Barut, Yildiz // Rheumatology International;Jan2006, Vol. 26 Issue 3, p191 

    The purpose of this study was to investigate whether negative effects of methotrexate (mtx) on blood homocysteine (hmc) levels can be prevented with the replacement of folic acid. 42 female patients with rheumatoid arthritis (RA) were studied. Patients were separated into two groups according to...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics