Cystic Fibrosis: Using genetic association to identify modifiers of disease variability in cystic fibrosis

Cutting, Garry R.
August 2006
European Journal of Human Genetics;Aug2006, Vol. 14 Issue 8, p890
Academic Journal
The article investigates the use of genetic association to identify modifiers of disease variability in cystic fibrosis by researchers from Baltimore, Maryland. Scientists have been puzzled why patients with the same disease can have different outcomes. It has been thought that the identification of the underlying causes of disease variation can be of considerable prognostic value. In this study, the severity of life-limiting pulmonary disease in cystic fibrosis patients is examined in relation to transforming growth factor beta-1 gene.


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