TITLE

Osteoporosis treatment: raloxifene (Evista) and stroke mortality

AUTHOR(S)
Wooltorton, Eric
PUB. DATE
July 2006
SOURCE
CMAJ: Canadian Medical Association Journal;7/18/2006, Vol. 175 Issue 2, p147
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article reports the increased risk of stroke mortality in women receiving raloxifene for the treatment and prevention of osteoporosis. The drug is a benzothiophene compound taken orally once a day. Its effects occur when the it binds tightly to estrogen receptors, that alters gene transcription in susceptible cells. Vasolidation and leg cramps are the common adverse effects of the drug. The other findings of the Raloxifene Use for the Heart trial are presented. Recommendations are given.
ACCESSION #
21678362

 

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