Family history and dysplastic nevi increased risk for multiple primary melanomas after an initial melanoma: COMMENTARY

McCarthy, William
May 2006
ACP Journal Club;May/Jun2006, Vol. 144 Issue 3, p77
Academic Journal
The article presents the author's views regarding a study related to multiple primary melanomas (MPM). The study includes a comprehensive literature review and confirms that second primary melanomas are more common in the same region of the body as the initial melanoma. It is estimated that the overall risk for MPM is 11%, taking into consideration that some people die from the first melanoma and are thus removed from further risk. However, the author states that the study failed to address factors, such as multiple non-dysplastic nevi, childhood exposure to excessive sunlight, immune status, or specific genetic analysis as contributing factors to the risk for multiple melanoma.


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