Oral mycophenolate led to more complete remissions than intravenous cyclophosphamide for active lupus nephritis: COMMENTARY

Walsh, Mike; Manns, Braden
May 2006
ACP Journal Club;May/Jun2006, Vol. 144 Issue 3, p74
Academic Journal
The article presents the author's views on a study regarding a comparative analysis between oral mycophenolate mofetil (MMF) and intravenous cyclophosphamide (IVC) for inducing remissions in active lupus nephritis. It is suggested that MMF is non-inferior to IVC for inducing remission in lupus nephritis, while resulting in fewer severe infections and a lower incidence of amenorrhea. The author reveals that this study provides further evidence that MMF may be at least similar to IVC for inducing remission in patients with diverse ethnic backgrounds without severe renal failure.


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