TITLE

A nonselective β-blocker did not prevent gastroesophageal varices in cirrhosis and portal hypertension: COMMENTARY

AUTHOR(S)
Korula, Jacob
PUB. DATE
May 2006
SOURCE
ACP Journal Club;May/Jun2006, Vol. 144 Issue 3, p68
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents comments of the author on a study, conducted by researcher R.J. Groszmann and colleagues, which found that a nonselective β-blocker did not prevent gastroesophageal varices in cirrhosis and portal hypertension. The pathophysiologic rationale for the study is that β-blocking drugs reduced portal pressure in human studies and prevented collateral vessels in experimental animals. The findings of this study show that formation of collateral vessels, although related to portal pressure, is not solved by β-blocking drugs.
ACCESSION #
21490788

 

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