TITLE

Review: Cardioselective β-blockers do not produce adverse respiratory effects in COPD: COMMENTARY

AUTHOR(S)
Lacasse, Yves
PUB. DATE
May 2006
SOURCE
ACP Journal Club;May/Jun2006, Vol. 144 Issue 3, p66
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents comments of the author on a study which found that cardioselective β-blockers do not produce adverse respiratory effects in COPD. The well-conducted meta-analysis by researchers of the study vividly illustrates one of the assumptions of the new paradigm of evidence-based medicine. For many clinicians, the suggestion that β-blockers may be safely used in COPD is counterintuitive. Only cardioselective β-blockers were assessed and the mean duration of the "long-term" studies included in the meta-analysis is too short to confirm absolute innocuousness of even cardioselective β-blockers in COPD.
ACCESSION #
21490784

 

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