Review: Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers prevent type 2 diabetes: COMMENTARY

Padwal, Raj
May 2006
ACP Journal Club;May/Jun2006, Vol. 144 Issue 3, p64
Academic Journal
The article presents comments of the author on a study which found that angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers prevent type 2 diabetes. Diabetes incidence may be reduced by renin-angiotensin inhibitors, increased by thiazides and β ;-blockers and largely unchanged by calcium-channel blockers. Evidence is required before renin-angiotensin inhibitors can be definitively considered to prevent diabetes. It is reasonable to prescribe renin-angiotensin inhibitors preferentially in patients at high risk for type 2 diabetes, who already require antihypertensive drug treatment and have no compelling indication for a different agent.


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