Intensive insulin therapy reduced cardiovascular disease in type 1 diabetes: COMMENTARY

Gerstein, Hertzel C.
May 2006
ACP Journal Club;May/Jun2006, Vol. 144 Issue 3, p63
Academic Journal
The article presents comments of the author on a study which determined that the long-term intensive insulin therapy (IIT) reduces cardiovascular disease (CVD) events in patients with type 1 diabetes. The Diabetes Control and Complications Trial showed that 6 years of IIT targeting normoglycemia markedly reduced diabetic retinopathy, nephropathy, and neuropathy in patients with type 1 diabetes. It was not designed to examine CVD events, although a trend toward reduced CVD events in the treatment group existed at the end of the active phase.


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