TITLE

Review: Antibiotic prophylaxis reduces mortality in patients with neutropenia after chemotherapy: COMMENTARY

AUTHOR(S)
Schuster, Mindy
PUB. DATE
May 2006
SOURCE
ACP Journal Club;May/Jun2006, Vol. 144 Issue 3, p57
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents comments of the author on the review of a study which found that antibiotic prophylaxis reduces mortality in patients with neutropenia after chemotherapy. The review showed a reduction in all-cause and infection-related mortality with antibiotic prophylaxis, particularly with a fluoroquinolone, compared with placebo or no intervention. This is the largest review to date on this topic Recent studies of fluoroquinolone prophylaxis showed decreased rates of fever and infection, but were not adequately powered for effects on mortality.
ACCESSION #
21490769

 

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