TITLE

Genetic Diversity of Invasive Strains of Haemophilus influenzae Type b before and after Introduction of the Conjugate Vaccine in Italy

AUTHOR(S)
Cerquetti, Marina; Cardines, Rita; Giufrè, Maria; Sofia, Tonino; D’Ambrosio, Fabio; Mastrantonio, Paola; Ciofi degli Atti, Marta Luisa
PUB. DATE
August 2006
SOURCE
Clinical Infectious Diseases;8/1/2006, Vol. 43 Issue 3, p317
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We determined the genotypes of 95 invasive Haemophilus influenzae type b (Hib) strains collected before and after introduction of widespread Hib vaccination in Italy. No substantial change in genetic diversity was highlighted by pulsed-field gel electrophoresis. However, an upward temporal trend in proportion of strains possessing multiple copies of the capsulation b locus was detected (P = .03).
ACCESSION #
21463535

 

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