TITLE

Positron emission tomography scanning is not superior to whole body multidetector helical computed tomography in the preoperative staging of colorectal cancer

AUTHOR(S)
Furukawa, H.; Ikuma, H.; Seki, A.; Yokoe, K.; Yuen, S.; Aramaki, I.; Yamaguchi, S.
PUB. DATE
July 2006
SOURCE
Gut;Jul2006, Vol. 55 Issue 7, p1007
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: The role of positron emission tomography with the glucose analogue [18F] fluoro-2-deoxy-D-glucose (FDG-PET) in the initial staging of disease in patients with primary colorectal cancer (CRC) has not been adequately assessed. Aims: To evaluate the additional value of FDG-PET as a staging modality, complementary to routine multidetector row computed tomography (MDCT) in patients with CRC. Methods: Forty four patients with CRC underwent preoperative MDCT and FDG-PET. The accuracy of intraoperative macroscopic staging was also investigated compared with histopathological diagnosis. All FDG-PET images were evaluated with respect to detectability of the primary tumour, lymph node involvement, and distant metastases. Both MDCT and FDG-PET diagnoses and treatment plan were compared with surgical and histopathological results. Results: Thirty seven patients underwent surgery. Tumour detection rate was 95% (42/44) for MDCT, 100% (44/44) for FDG-PET, and 100% (37/37) for intraoperative macroscopic diagnosis. Pathological diagnosis of T factor was T1 in five, T2 in four, T3 in 24, and T4 in four cases. Concordance rate with pathological findings of T factor was 57% (21/37) for MDCT and 62% (23/37) for macroscopic diagnosis. Lymph node involvement was pathologically positive in 19 cases. Regarding N factor, overall accuracy was 62% (23/37) for MDCT, 59% (22/37) for FDG-PET, and 70% (26/37) for macroscopic diagnosis. For all 44 patients, FDG-PET findings resulted in treatment changes in only one (2%) patient. Conclusion: FDG-PET is not superior to routine MDCT in the initial staging of primary CRC.
ACCESSION #
21399630

 

Related Articles

  • Intense [18F]FDG tongue uptake in a case of acipimox-related angio-oedema during FDG-PET myocardial viability study. Arsos, Georgios; Weijs, Leo; de Haas, Marie; de Vrey, Evelyn; de Klerk, John // European Journal of Nuclear Medicine & Molecular Imaging;Aug2007, Vol. 34 Issue 8, p1320 

    The article presents diagnostic images showing intense fluorodeoxyglucose (FDG) tongue uptake in the case of acipimox-related angio-edema during FDG-positron emission tomography (PET) myocardial viability study.

  • Pozitronska emisiona tomografija sa kompjuterizovanom tomografijom u dijagnostici nepoznatog primarnog karcinoma. Lučić, S. M.; Lučić, M. A.; Peter, A.; Jovanović, D.; Vučaj-Ćirilović, V. // Acta Chirurgica Iugoslavica;2009, Vol. 56 Issue 4, p159 

    Cancer of unknown primary origin is not an uncommon clinical state, usually accounting for 2%-7% of all cancer patients. Material and methods: Positron emission tomography and computed tomography (PET/CT) was performed in 17 patients with histologically proven metastatic tumors of unknown...

  • 18F-florbetaben Aβ imaging in mild cognitive impairment. Ong, Kevin; Villemagne, Victor L.; Bahar-Fuchs, Alex; Lamb, Fiona; Chételat, Gaël; Raniga, Parnesh; Mulligan, Rachel S.; Salvado, Olivier; Putz, Barbara; Roth, Katrin; Masters, Colin L.; Reininger, Cornelia B.; Rowe, Christopher C. // Alzheimer's Research & Therapy;2013, Vol. 5 Issue 1, p1 

    Introduction: 18F-florbetaben and positron emission tomography were used to examine the relationships between β-amyloid (Aβ) deposition, cognition, hippocampal volume, and white matter hyperintensities in mild cognitive impairment (MCI). Methods: Forty-five MCI participants were evaluated....

  • POSITRON EMISSION TOMOGRAPHY, PELVIS. Schnell, Zoanne Burgess; Van Leeuwen, Anne M.; Kranpitz, Todd R. // Davis's Comprehensive Handbook of Laboratory & Diagnostic Tests ;Jan2003, p807 

    Presents a comprehensive guide to positron emission tomography (PET) of the pelvis. Purpose of PET; Indications; Nursing implications and procedure.

  • Vision and Mission in Medical Imaging Hybrid Imaging: A New Frontier in Medical Imaging. Bijan, Bijan // Iranian Journal of Radiology;2010, Vol. 7 Issue 2, p114 

    The article discusses the importance of hybrid imaging in the in the future of medical diagnostics. The author examines the impact of the technology on medical practice and the conflict among medical practitioners in operating positron emission tomography (PET)-computed tomography (CT). It...

  • Positron emission tomography versus positron emission tomography/computed tomography: from “unclear” to “new-clear” medicine. von Schulthess, Gustav K. // Molecular Imaging & Biology;Jul2004, Vol. 6 Issue 4, p183 

    PET/CT is a new diagnostic imaging modality, which proves that adding PET and CT is not merely additive, but highly synergistic. While PET provides high sensitivity for lesion detection, CT provides the anatomic backdrop, which frequently is important in order to make a specific diagnosis. CT...

  • POSITRON EMISSION TOMOGRAPHY, BRAIN. Schnell, Zoanne Burgess; Van Leeuwen, Anne M.; Kranpitz, Todd R. // Davis's Comprehensive Handbook of Laboratory & Diagnostic Tests ;Jan2003, p800 

    Presents a comprehensive guide to positron emission tomography (PET) of the brain. Purpose of PET; Indications; Nursing implications and procedure.

  • Neuroimaging Techniques as a New Tool to Study the Neural Correlates Involved in Human Male Sexual Arousal. Mouras, Harold // Current Medical Imaging Reviews;2006, Vol. 2 Issue 1, p71 

    During the last five years, neuroimaging techniques such as Positron Emission Tomography (PET) and functional Magnetic Resonance Imaging (fMRI) appeared as new tools to study the neural correlates of human male sexual arousal (SA). In this paper, some of the main methodological aspects of these...

  • Contributions of Functional Neuroimaging to Clinical and Cognitive Neuropsychology: A Selective Review. Chokron, Sylvie // Current Medical Imaging Reviews;2006, Vol. 2 Issue 1, p59 

    Functional neuroimaging has provided a new view of the activity in the human cortex. The understanding of the relationship between functional signals, particularly functional MRI, clinical disorders and cognitive functions has increased. This article reviews selected contributions of positron...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics