Hedgehog Wnteraction in colorectal cancer

van den Brink, G. R.; Hardwick, J. C. H.
July 2006
Gut;Jul2006, Vol. 55 Issue 7, p912
Academic Journal
The Hedgehog pathway was recently shown to antagonise constitutive activity of the Wnt pathway that drives proliferation of colorectal cancer cells. Studies in this issue of Gut refine our understanding of the underlying mechanism and provide evidence for such antagonism in colorectal cancers in vivo.


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