Application of anodized aluminum in fluorescence detection of biological species

Takmakov, Pavel; Vlssiouk, Ivan; Smirnov, Sergei
August 2006
Analytical & Bioanalytical Chemistry;Aug2006, Vol. 385 Issue 5, p954
Academic Journal
Thin nanoporous alumina obtained by anodization of aluminum films offers promising advantages for application in fluorescence-based biological sensors including convenient preparation, increased density of binding sites, and improved collection efficiency of fluorescence. These advantages are illustrated in the detection of streptavidin using biotin covalently bound to the surface of alumina nanopores. Fluorescence intensity enhancement as high as 7 times is observed in nanopores in comparison to flat glass surface. [Figure not available: see fulltext.]


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