TITLE

Asian experience with the Pintucci keratoprosthesis

AUTHOR(S)
Maskati, Quresh B.; Maskati, B T
PUB. DATE
June 2006
SOURCE
Indian Journal of Ophthalmology;Jun2006, Vol. 54 Issue 2, p89
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Purpose: To report the outcome of a retrospective study of the Pintucci Biointegrable Keratoprosthesis (PBIKP) in Asian eyes.Materials and Methods: This was a retrospective analysis of 31 eyes of 31 consecutive patients, who underwent surgery with implantation of the PBIKP. The age ranged from 7 years to 65 years, with a mean age of 34 years. The indications for the PBIKP were chemical burns (11 cases); highly vascularized failed grafts (11 cases); severe dry eyes with total vascularized cornea (6 cases); miscellaneous (3 cases). Twenty eight bilaterally blind Asian patients, with vision not exceeding hand motion close to face in the better eye, underwent the classical two-stage procedure to implant the PBIKP. In another three patients, the PBIKP was implanted as a one-stage procedure. All 31 eyes were unsuitable for keratoplasty or had repeated failed keratoplasties. All patients were followed up for periods ranging from 6 months to 7 years, with a mean of 3.2 years.Results: No eye had infection or retro prosthetic membrane, which were common complications in other Keratoprostheses designs. Twenty-four of 31 eyes improved to greater than finger counting at 1.5 metres, enabling the patients to function independently. Four of 31 eyes (13%) improved to 20/200 or better. Twelve of 31 eyes had significant complications. However only a few were vision- threatening.Conclusion: With careful patient selection, the PBIKP could prove to be a useful modality of treatment for bilaterally corneally blind Asian patients, whose vision cannot be improved with conventional medical or surgical treatments.
ACCESSION #
21277662

 

Related Articles

  • Panel discusses advances, limits of corneal surgery.  // Ophthalmology Times;10/15/2000, Vol. 25 Issue 20, p1 

    Deals with a panel discussion among corneal surgery experts regarding developments in corneal surgery. Impact of the progress in understanding the genetic basis of corneal disease on procedures of corneal surgery; Scientific advances and regulatory constraints affecting corneal transplantation;...

  • Corneal replacement using a synthetic hydrogel cornea, AlphaCor[trademark]: device, preliminary outcomes and complications. Hicks, C R; Crawford, G J; Lou, X; Tan, D T; Snibson, G R; Sutton, G; Downie, N; Werner, L; Chirila, T V; Constable, I J // Eye;Apr2003, Vol. 17 Issue 3, p385 

    Purpose Clinical assessment of outcome of corneal replacement with a synthetic cornea, AlphaCor[SUPTM], in patients considered at too high risk for conventional penetrating keratoplasty with donor tissue to be successful, but excluding indications such as end-stage dry eye that might be suited...

  • Incision key to ring segment procedure, outcomes. McDonald II, James E.; Waring III, George O. // Ophthalmology Times;02/15/2001, Vol. 26 Issue 4, p7 

    Highlights the significance of corneal incision management to the implantation of intrastromal corneal rings. Comparison between the tectonics of the cornea and rubber band; Problems arising from lapses in incision.

  • No clinical advantage to larger diameter grafts in DSAEK. Correa, Mark; Hasson, Matt // Ocular Surgery News;1/25/2012, Vol. 30 Issue 2, p25 

    The article reports that the diameter of the donor graft does not play a key role in postoperative endothelial cell counts in the two years after performing Descemet's stripping automated endothelial keratoplasty (DSAEK) based on the comparative analysis of an interventional case series.

  • Prolongation of corneal allograft survival by CTLA4-FasL in a murine model. Weiyun Shi // Graefe's Archive of Clinical & Experimental Ophthalmology;Nov2007, Vol. 245 Issue 11, p1691 

    Abstract Background  To investigate the therapeutic effect of CTLA4-FasL—B7 costimulatory pathway blockage—on graft survival in a murine model of corneal transplantation. Methods  Orthotopic penetrating keratoplasty was performed on...

  • Eye bank organ culture tissue may minimize detachment rate in DMEK. Boyle, Erin L.; Cimberle, Michela; Mullin, David W. // Ocular Surgery News;7/10/2010, Vol. 28 Issue 13, p20 

    The article discusses a study by Friedrich E. Kruse which investigated the association between using organ culture tissue and a decrease in the detachment rate after Descemet's membrane endothelial keratoplasty.

  • Corneal Thickness as Predictor Of Corneal Transplant Outcome. Verdier, D.; Sugar, A.; Baratz, K.; Beck, R. // Review of Ophthalmology;Jul2013, Vol. 20 Issue 7, p69 

    The article reports on thickness of cornea thickness that can serve as a predictor of corneal graft success after the first five years of penetrating keratoplasty.

  • "Small bubble technique" helps "big bubble technique". Price Jr., Francis W. // British Journal of Ophthalmology;Oct2007, Vol. 91 Issue 10, p1260 

    The author reflects on the significance of operating microscope and monofilament sutures in corneal transplant surgery. These new transplantation techniques include endothelial keratoplasty (EK), femtosecond keratoplasty (PK) and anterior lamellar keratoplasty (ALK). He noted that these...

  • Graft dislocation after DSAEK linked to previous glaucoma surgery.  // Ocular Surgery News;11/10/2012, Vol. 30 Issue 21, p50 

    The article discusses a study by Jeffrey M. Goshe and colleagues which revealed that patients who underwent Descemet's Stripping automated endothelial keratoplasty after glaucoma surgery, face higher rate of graft dislocation as compared to those without surgery. It also showed that graft...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics