One-year Outcomes of Epi-LASIK for Myopia

Jinhui Dai; Renyuan Chu; Xingtao Zhou; Chongda Chen; Xiaomei Qu; Xiaoying Wang
June 2006
Journal of Refractive Surgery;Jun2006, Vol. 22 Issue 6, p589
Academic Journal
PURPOSE: To evaluate the early clinical outcomes of epi-LASIK for myopia. METHODS: This study comprised 302 eyes of 162 patients. Epi-LASIK was performed with an automatically rotational epikeratome (KM-5000D). Epithelial separation was achieved mechanically without the use of alcohol. After laser ablation, the epithelial sheet was repositioned and a therapeutic contact lens was applied to the cornea immediately for 3 to 5 days. Postoperative visual acuity, symptoms, epithelial sheet, contrast sensitivity, wavefront aberration, and haze formation were evaluated 3, 6, and 12 months postoperatively. RESULTS: Of the 302 eyes, 72 eyes (42 patients) with a mean spherical equivalent refraction of -9.13±4.23 diopters (D) (range: -1.25 to -19.0 D) had >1-year follow-up. One eye failed to make the epithelial sheet because of the narrow palpebral fissure. An integrated epithelial sheet with a diameter of 8 to 9 mm was made in 289 (95.7%) eyes, leaving a superior hinge of approximately 2 to 4 mm. In 1 eye, stromal tissue remained in the epithelial sheet. Free epithelial flaps were made in 12 (4%) eyes. Mild discomfort was reported by 150 patients (282 eyes, 93.4%). Twelve patients (20 eyes, 6.6%) reported moderate symptoms. At 1 day postoperatively, corneal epithelium was almost transparent or had mild focal edema in 288 (95.4%) eyes; moderate edema was reported in 14 (4.6%) eyes. At 1 year postoperatively, spherical equivalent refraction of 60 (83.3%) eyes was within ±1.0 D of attempted refraction. Grade 0.5 haze was found in 2 eyes; all other eyes had no haze. No eye lost any lines of best spectacle-corrected visual acuity (BSCVA), whereas 12 (16.7%) of 72 eyes gained one or two lines of BSCVA. Contrast sensitivity decreased 1 month postoperatively and was restored to preoperative levels in eyes with preoperative spherical equivalent refraction <-10.0 D. Higher order aberration increased significantly postoperatively. CONCLUSIONS: Epi-LASIK is a safe and efficient method to correct myopia with the advantage that it has only mild symptoms and mild haze. A larger study with longer follow-up is needed to determine its long-term clinical outcomes.


Related Articles

  • Photorefractive Keratectomy and LASIK for the Correction of Hyperopia: 2-year Follow-up. Spadea, Leopoldo; Sabetti, Lelio; D'Alessandri, Laura; Balestrazzi, Emilio // Journal of Refractive Surgery;Feb2006, Vol. 22 Issue 2, p131 

    PURPOSE: To evaluate the efficacy and safety of photorefractive keratectomy (PRK) and LASIK in the correction of hyperopia. METHODS: A retrospective study was conducted on 100 eyes of 56 patients with a mean hyperopia of +2.85±1.1 diopters (D) undergoing PRK and 100 eyes of 50 patients with a...

  • Femtosecond Laser Flap Creation for Laser in situ Keratomileusis: Six-month Follow-up of Initial U.S. Clinical Series. Nordan, Lee T.; Slade, Stephen G.; Baker, Richard N.; Suarez, Carlos; Juhasz, Tibor; Kurtz, Ron // Journal of Refractive Surgery;Jan2003, Vol. 19 Issue 1, p8 

    PURPOSE: To evaluate clinical performance of a femtosecond laser for flap creation in laser in situ keratomileusis (LASIK). METHODS: A prospective, consecutive series of 208 eyes (122 patients) undergoing LASIK between June 2000 and November 2000 using a femtosecond laser for creation of the...

  • Comparison of NIDEK CATz Wavefront-guided LASIK to Traditional LASIK With the NIDEK CXII Excimer Laser in Myopia. Rui He; Min Qu; Shun Yu // Journal of Refractive Surgery;Sep2005 Supplement, pS646 

    PURPOSE: To compare the visual and refractive outcomes in myopic LASIK between wavefront-guided and traditional treatment. METHODS: The study included 162 eyes of 81 myopic patients undergoing LASIK by one surgeon. The right eye of each patient underwent customized LASIK with the NIDEK NAVEX...

  • Combined Flap Undersurface and Bed LASIK for High Myopia. Li Wei Li; Wang Qin Mei; Fang Xue Jun // Journal of Refractive Surgery;Sep2005 Supplement, pS606 

    PURPOSE: To discuss the predictability, stability, and safety of LASIK for high myopia using laser treatment on both the flap undersurface and bed (both-sided LASIK). METHODS: One hundred twenty-one eyes of 63 patients underwent flap undersurface and bed LASIK for high myopia. Postoperative...

  • Study: custom LASIK, PRK superior to standard procedures. Charters, Lynda; Tauber, Shachar // Ophthalmology Times;9/1/2004, Vol. 29 Issue 17, p33 

    Presents the result of the study that compared standard LASIK eye surgery with LADAR-vision CustomCornea to treat myopia with minimal astigmatism. Use of standard methods for all conventional and customized treatments; Evaluation of uncorrected visual acuity one month after the LASIK procedures;...

  • Do outside temperature and sunlight duration influence the outcome of laser refractive surgery? Results from the Hamburg Weather Study. Neuhaus-Richard, Ines; Frings, Andreas; Görsch, Isabel Caroline; Druchkiv, Vasyl; Katz, Toam; Linke, Stephan Johannes; Richard, Gisbert // Clinical Ophthalmology;2014, Vol. 8, p1129 

    Purpose: To examine the impact of temperature and sunlight duration on refractive and visual outcome of laser-assisted in situ keratomileusis (LASIK) in myopic eyes. Setting: University Medical Center Hamburg-Eppendorf, Germany, and Care Vision Refractive Centers, Germany. Design: Retrospective,...

  • Laser in situ Keratomileusis for Compound Myopic Astigmatism Using the Meditec MEL 70 G-Scan Excimer Laser. Uçakhan, Ömür Ö. // Journal of Refractive Surgery;Mar2003, Vol. 19 Issue 2, p124 

    PURPOSE: To determine the safety, efficacy, predictability, and stability of laser in situ keratomileusis (LASIK) in treating patients with myopic astigmatism using the Meditec MEL 70 G-Scan excimer laser. METHODS: Seventy-four eyes of 42 patients with myopia ranging from -4.50 to -9.88 D and...

  • Questions help determine when enhancements are warranted. Bowers, Lois A. // Ophthalmology Times;10/15/2007, Vol. 32 Issue 20, p46 

    The article provides information concerning important points to consider before using the laser to perform enhancements after LASIK, lamellar surgery, incisional surgery, and corneal surgery. The important points to consider include determining the patients goal, knowing the best-corrected...

  • Wavefront-guided refractive surgery results of training-surgeons. STILLITANO, IANE; YAMAZAKI, ESTER; MELO JR., LUIZ ALBERTO; BOTTOS, JULIANA; CAMPOS, MAURO // Arquivos Brasileiros de Oftalmologia;2010, Vol. 73 Issue 4, p323 

    Purpose: To assess clinical outcomes and changes on higher-order aberrations (HOA) after wavefront-guided laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) for correction of myopia and myopic astigmatism performed by training-surgeons. Methods: One hundred and seventy...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics