Cerebellar hypermetabolism in paraneoplastic cerebellar degeneration

Choi, K-D.; Kim, J. S.; Park, S-H.; Kim, Y. K.; Kim, S. E.; Smitt, P. S.
April 2006
Journal of Neurology, Neurosurgery & Psychiatry;Apr2006, Vol. 77 Issue 4, p525
Academic Journal
A 51 year old man with paraneoplastic cerebellar degeneration from gastric adenocarcinoma showed cerebellar hypermetabolism and increased perfusion on brain FDG-PET scan and SPECT during the acute stage of his illness. The patient underwent subtotal gastrectomy. The intensity of the hypermetabolism had decreased markedly on follow-up FDG-PET 3 months later following two cycles of chemotherapy. We suggest that the cerebellar hypermetabolism may have been due to an acute inflammatory process associated with an immunological reaction.


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