Prospective randomized trial to evaluate effectiveness of periprostatic nerve block in prostatic biopsy

Lavania, P.; Dubey, D.; Khurana, N.; Mandhani, A.; Kapoor, R.; Srivastava, A.; Kumar, A.
January 2006
Indian Journal of Urology;Jan-Mar2006, Vol. 22 Issue 1, p39
Academic Journal
OBJECTIVES: The objective of the study was to evaluate the efficacy of local anesthetic infiltration, in decreasing the discomfort experienced by patients undergoing transrectal ultrasound (TRUS) guided biopsy of prostate. MATERIALS AND METHODS: Between January 2002 and February 2003, we investigated consecutively, asymptomatic men, suspected of having prostatic cancer. About 39 patients were randomized to receive 10 ml of 2% Lidocaine periprostatic block + intrarectal Lidocaine gel (group 1 = 20), or intarectal Lidocaine gel only (group 2 = 19) during prostatic biopsy. Immediately following the TRUS-guided biopsy, patients were asked to grade the pain they experienced using the 11-point visual analogue score (VAS). RESULTS: The mean pain score in the patients of group 1 were significantly lower than the patients of group 2 (P<0.001), suggesting that periprostatic block produced a significant reduction in the perceived pain. CONCLUSIONS: Local anesthetic infiltration by TRUS-guided injection of Lidocaine is effective for decreasing pain associated with prostatic biopsy.


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