TITLE

Universal Genotyping in Tuberculosis Control Program, New York City, 2001-2003

AUTHOR(S)
Clark, Carla M.; Driver, Cynthia R.; Munsiff, Sonal S.; Driscoll, Jeffrey R.; Kreiswirth, Barry N.; Zhao, Benyang; Ebrahimzadeh, Adeleh; Salfinger, Max; Piatek, Amy S.; Abdelwahab, Jalaa'
PUB. DATE
May 2006
SOURCE
Emerging Infectious Diseases;May2006, Vol. 12 Issue 5, p719
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In 2001, New York City implemented genotyping to its tuberculosis (TB) control activities by using IS6110 restriction fragment length polymorphism (RFLP) and spoligotyping to type isolates from culture-positive TB patients. Results are used to identify previously unknown links among genotypically clustered patients, unidentified sites of transmission, and potential false-positive cultures. From 2001 to 2003, spoligotype and IS6110-based RFLP results were obtained for 90.7% of eligible and 93.7% of submitted isolates. Fifty-nine (2.4%) of 2,437 patient isolates had false-positive culture results, and 205 genotype clusters were identified, with 2-81 cases per cluster. Cluster investigations yielded 57 additional links and 17 additional sites of transmission. Four additional TB cases were identified as a result of case finding initiated through cluster investigations. Length of unnecessary treatment decreased among patients with false-positive cultures.
ACCESSION #
20658665

 

Related Articles

  • Tuberculosis screening and follow-up of asylum seekers in Norway: a cohort study. Harstad, Ingunn; Heldal, Einar; Steinshamn, Sigurd L.; Garåsen, Helge; Jacobsen, Geir W. // BMC Public Health;2009, Vol. 9 Issue 1, p1 

    Background: About 80% of new tuberculosis cases in Norway occur among immigrants from high incidence countries. On arrival to the country all asylum seekers are screened with Mantoux test and chest x-ray aimed to identify cases of active tuberculosis and, in the case of latent tuberculosis, to...

  • Analysis of genetic predisposition to pulmonary tuberculosis in native Russians. Gra, O. A.; Kozhekbaeva, Zh. M.; Skotnikova, O. I.; Litvinov, V. I.; Nasedkina, T. V. // Russian Journal of Genetics;Feb2010, Vol. 46 Issue 2, p230 

    Tuberculosis (TB) is one of the most important concerns of public health. There is evidence suggesting that genetic status is responsible for predisposition to infectious diseases including TB. To determine genetic risk factors of TB development, the frequencies of polymorphisms of genes CYP1A1,...

  • Public Health Then and Now: An Historical Repository. Rosenkrantz, Barbara Gutmann // American Journal of Public Health;Dec1985, Vol. 75 Issue 12, p1376 

    The article reports that the "American Journal of Public Health" has made history over the past year in the U.S. Much of the research is the work of social historians who have recently turned to the study and analysis of health and disease in populations to understand fundamental processes of...

  • Factors contributing to the cause of a community outbreak of tuberculosis. Doyle, Y. G.; Graves, P.; Rayner, C.; Gerada, C.; Wakefield, D. // Journal of Public Health;Jun2004, Vol. 26 Issue 2, p193 

    The diagnosis of pulmonary tuberculosis (TB) in a nursery teacher led to a total of 282 adults and children being screened for TB, and 67 of these contracted the condition. Latent and active factors mitigated against earlier diagnosis of the disease during the multiple contacts by the teacher...

  • A expansão do tratamento supervisionado (TS) para o controle da tuberculose na Paraíba (1999/2005). de Oliveira Rodrigues, Gianne; de Sá, Lenilde Duarte; de Almeida Nogueira, Jordana; Damascena, Lecidâmia Cristina Leite; Gomes, Anna Luiza Castro; Villa, Tereza Cristina Scatena // Revista Eletronica de Enfermagem;2008, Vol. 10 Issue 3, p632 

    The supervised treatment (TS) is a pillar of the DOTS strategy (Directly Observed Treatment Short-course) and its adoption has been recommended for the control of tuberculosis (TB). The study aimed to analyze the strengths and weaknesses in the expansion process of the supervised treatment in...

  • Combination of Host Susceptibility and Virulence of Mycobacterium tuberculosis Determines Dual Role of Nitric Oxide in the Protection and Control of Inflammation. Beisiegel, Martin; Kursar, Mischo; Koch, Markus; Loddenkemper, Christoph; Kuhlmann, Stefanie; Zedler, Ulrike; Stäber, Manuela; Hurwitz, Robert; Kaufmann, Stefan H. E. // Journal of Infectious Diseases;4/15/2009, Vol. 199 Issue 8, p1222 

    Tuberculosis (TB) remains a global health threat. Although it is generally accepted that TB results from intensive cross-talk between the host and the pathogen Mycobacterium tuberculosis, underlying mechanisms remain elusive. The first evidence of human polymorphisms related to susceptibilities...

  • Screening for tuberculosis among 2381 household contacts of sputum-smear-positive cases in The Gambia. Jackson-Sillah, Dolly; Hill, Philip C.; Fox, Annette; Brookes, Roger H.; Donkor, Simon A.; Lugos, Moses D.; Howie, Stephen R.C.; Fielding, Katherine R.; Jallow, Adama; Lienhardt, Christian; Corrah, Tumani; Adegbola, Richard A.; McAdam, Keith P. // Transactions of the Royal Society of Tropical Medicine & Hygiene;Jun2007, Vol. 101 Issue 6, p594 

    Summary: Contact investigation is a key component of tuberculosis (TB) control in developed, but not developing, countries. We aimed to measure the prevalence of TB among household contacts of sputum-smear-positive TB cases in The Gambia and to assess the sensitivity of an enzyme-linked...

  • A comparative examination of tuberculosis immigration medical screening programs from selected countries with high immigration and low tuberculosis incidence rates. Alvarez, Gonzalo G.; Gushulak, Brian; Rumman, Khaled Abu; Altpeter, Ekkehardt; Chemtob, Daniel; Douglas, Paul; Erkens, Connie; Helbling, Peter; Hamilton, Ingrid; Jones, Jane; Matteelli, Alberto; Paty, Marie-Claire; Posey, Drew L.; Sagebiel, Daniel; Slump, Erika; Tegnell, Anders; Val&;#x00ED;n, Elena Rodríguez; Winje, Brita Askeland; Ellis, Edward // BMC Infectious Diseases;2011, Vol. 11 Issue 1, p1 

    Background: Tuberculosis (TB) in migrants is an ongoing challenge in several low TB incidence countries since a large proportion of TB in these countries occurs in migrants from high incidence countries. To meet these challenges, several countries utilize TB screening programs. The programs...

  • Genotypic Diversity among Isoniazid-Resistant Isolates of Mycobacterium tuberculosis from Rashid Hospital in Dubai, United Arab Emirates. S. Ahmad; E. Fares // Medical Principles & Practice;Jan/Feb2005, Vol. 14 Issue 1, p16 

    Objective: To perform molecular fingerprinting for strain relatedness among isoniazid-resistant Mycobacterium tuberculosis isolates recovered from tuberculosis (TB) patients in the United Arab Emirates (UAE). Materials and Methods: Thirty-two consecutive isoniazid-resistant M. tuberculosis...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics