TITLE

Influence of hematocrit and pump prime on cerebral oxygen saturation in on-pump coronary revascularization

AUTHOR(S)
McCusker, Kevin; Chalafant, Anthony; de Foe, Gordon; Gunaydin, Serdar; Vijay, Venkataramana
PUB. DATE
May 2006
SOURCE
Perfusion;May2006, Vol. 21 Issue 3, p149
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: The couplings between cerebral oxygenation (rSO2), on-pump hematocrit and circuit prime are explored in this study. Methods: Thirty-eight consecutive patients undergoing coronary revascularization with cardiopulmonary bypass (CPB) were matched on preoperative hematocrit <40% and >40% (n = 16). Similarly, six blood prime patients were matched with six crystalloid prime patients. Hematocrit and rSO2 levels were then compared on CPB. Results: The pre-operative hematocrit >40% group retained higher levels on pump run (p <0.01) and significantly higher rSO2 prior to CPB (64.8±9.6 versus 73.2±7.3), and on and off CPB (61.1±8.8 versus 67.4±6.4). Blood priming increased absolute rSO2 (2.3±6.3 versus -10.9±5.9) and % rSO2 (4.7±11.8 versus -14.2±7.4%) in the low hematocrit group. Conclusion: Blood primes are instrumental in high-risk and low preoperative hematocrit patients in preventing cerebral oxygen desaturation during initiation and maintenance of CPB.
ACCESSION #
20619049

 

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