TITLE

Ovo/svb integrates Wingless and DER pathways to control epidermis differentiation

AUTHOR(S)
Payre, Francois; Vincent, Alain; Carreno, Sebastien
PUB. DATE
July 1999
SOURCE
Nature;7/15/1993, Vol. 400 Issue 6741, p271
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Demonstration that in Drosophila, the expression of the ovo/shavenbaby (svb) gene controls the choice between the fates of smooth cells and the denticles. Finding that svb is a key selector gene that, cell autonomously, directs cytoskeletal modifications producing the denticle; How the Drosophila epidermal growth factor (EGF) receptor (DER) pathway promotes denticle formation by activating svb expression; How Wingless promotes the smooth cell fate through the transcriptional repression of svb by the bipartite nuclear factor Armadillo/dTcf.
ACCESSION #
2042349

 

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics