TITLE

Lack of Association between Infection with a Novel Human Coronavirus (HCoV), HCoV-NH, and Kawasaki Disease in Taiwan

AUTHOR(S)
Luan-Yin Chang; Bor-Luen Chiang; Chuan-Liang Kao; Mei-Hwan Wu; Pei-Jer Chen; Berkhout, Ben; Hui-Ching Yang; Li-Min Huang
PUB. DATE
January 2006
SOURCE
Journal of Infectious Diseases;1/15/2006, Vol. 193 Issue 2, p283
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We investigated whether infection with a novel human coronavirus (HCoV), called ‘New Haven coronavirus’ (HCoV-NH)-which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63-is associated with Kawasaki disease (KD) in Taiwan. Fifty-three patients with KD were enrolled in our study. Serum, peripheral-blood mononuclear cells, nasopharyngeal aspirates, throat swabs, and rectal swabs from these patients were assayed for HCoV-NL63 by real-time reverse-transcriptase (RT) polymerase chain reaction (PCR), and the throat swabs, nasopharyngeal aspirates, and rectal swabs were also assayed for HCoV-NH by RT-PCR. All PCR results were negative for both HCoV-NL63 and HCoV-NH; therefore, we did not find any association between HCoV-NH infection and KD in Taiwan.
ACCESSION #
20371927

 

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