TITLE

A prospective clinical study of cerebral microemboli and neuropsychological outcome comparing vent-line and auto-venting arterial line filters: both filters are equally safe

AUTHOR(S)
Whitaker, Donald C.; Stygall, Jan; Hope-Wynne, Chris; Walesby, Robin K.; Harrison, Michael J. G.; Newman, Stanton P.
PUB. DATE
March 2006
SOURCE
Perfusion;Mar2006, Vol. 21 Issue 2, p83
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Introduction: Microemboli are the main implicated cause of neuropsychological (NP) impairment after cardiac surgery. This prospective clinical trial compared the effect of an auto-venting arterial line filter on intraoperative cerebral microemboli and NP outcome compared to an arterial line filter with a vent line, in patients undergoing elective coronary artery bypass graft (CABG) surgery.Methods: One hundred and ten patients received either an Avecor Affinity (n = 73) or Pall AV-6 (n=37) control filter. Cerebral microemboli during cardiopulmonary bypass were recorded by transcranial Doppler monitoring of the right middle cerebral artery. Evidence of cerebral impairment was obtained by comparing patients' performance in a NP test battery (nine tests) administered 6–8 weeks postoperatively with their preoperative scores.Results: During cardiopulmonary by-pass, the median number and range of microemboli were 67 (5–846) and 55 (2–773) for the Avecor and AV-6 groups, respectively (p=0.47). There was no difference in NP outcome.Conclusion: There is no difference in the filtering ability of vent-line and auto-vent filters as assessed by cerebral microemboli. This, together with the similar NP outcome, suggests that both types of filter are equally safe for clinical use.
ACCESSION #
20338365

 

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