COMMENTARY: Incidence of end-stage renal disease in patients with type 1 diabetes was 7.8% at 30 years after diagnosis

Winkelmayer, Wolfgang C.
March 2006
ACP Journal Club;Mar/Apr2006, Vol. 144 Issue 2, p51
Academic Journal
This article reports that researchers describes the natural history of incident patients with type 1 diabetes for more then 30 years. While one could assume that the availability of new treatment approaches would improve the long-term prognosis of patients with diabetes over time. Patients who were diagnosed with type 1 diabetes 40 years ago seem to have had an increased risk for end-stage renal disease (ESRD) in each 5-year period after diagnosis compared with patients diagnosed more recently. However, this trend was not tested statistically. Because the length of follow-up differed for each vintage cohort and the rates of death and ESRD were not constant across the follow-up periods, comparisons of these outcomes among vintage cohorts are difficult to interpret, even when the analysis is adjusted for other explanatory variables.


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