900 mg daily of gabapentin was effective for hot flashes in women with breast cancer

March 2006
ACP Journal Club;Mar/Apr2006, Vol. 144 Issue 2, p41
Academic Journal
This article presents a study which states that 900 mg daily of gabapentin was effective for hot flashes in women with breast cancer. In the study, 420 women 18 years of age with breast cancer who were having an average 2 hot flashes daily. 71% of women were taking tamoxifen. Women receiving chemotherapy or taking venlafaxine, clonidine, or anticonvulsants were not eligible, but use of other antidepressants was allowed. Exclusion criteria included pregnancy; breastfeeding; use of steroidal contraception; and recent history of cardiovascular, cerebrovascular, hepatic, or renal problems.


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