COMMENTARY: Direct decompressive surgery plus radiotherapy improved the ability to walk in spinal cord compression caused by metastatic cancer

Marmor, Eric
March 2006
ACP Journal Club;Mar/Apr2006, Vol. 144 Issue 2, p38
Academic Journal
This article reports that the landmark study by researchers investigated the role of direct decompressive resection in the treatment of metastatic epidural spinal cord compression. In the study, 101 patients were entered over 10 years before the study was terminated because the criterion of a predetermined stopping rule was met. More patients in the surgery plus postoperative radiation group retained the ability to walk and walked longer than did those in the radiation-alone group. Furthermore, surgery-group patients had better continence and muscle strength, longer overall survival, and lower requirements for opioid analgesics and steroids.


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