First-line treatment with colchicine reduced recurrent pericarditis

March 2006
ACP Journal Club;Mar/Apr2006, Vol. 144 Issue 2, p31
Academic Journal
The article focuses on a study which revealed that first-line treatment with colchicine reduced recurrent pericarditis. Nearly 84 patients were observed who had a first recurrence of pericarditis and previous idiopathic, viral and autoimmune causes of the first episode of acute pericarditis. Conventional therapy consisted of aspirin, 800 mg every 6 or 8 hours for 7 to 10 days, then tapered for 3 to 4 weeks. Patients in whom aspirin was contraindicated received prednisone, 1.0 to 1.5 mg/kg per day for 4 weeks, then tapered gradually.


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