Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD 15 3020insC mutation?
- NOD takes its toll but stays in the CARDs in Crohn’s disease. Luft, Friedrich // Journal of Molecular Medicine;Aug2005, Vol. 83 Issue 8, p577
Points out to the growing body of evidence implicating nucleotide-binding oligomerization domain (NOD) 2 and toll-like receptor (TLR) 4 mutations in Crohn's disease. Occurrence of inflammatory bowel diseases in areas of the gastrointestinal tract with the highest numbers of luminal bacteria;...
- REGIONAL ENTERITIS. Berger, Samuel S. // American Journal of Gastroenterology;Jul1956, Vol. 26 Issue 1, p81
Presents a case of a patient with regional enteritis. Persistence of abdominal pains suffered by the patient; Examination of the abdomen of the patient; Pathology of the regional enteritis.
- Small bowel length in Crohn's disease. Glehen, O.; Lifante, J. C.; Vignal, J.; Francois, Y.; Gilly, F. N.; Flourié, B.; Descos, L.; Chung, R. J. H.; Mithieux, F. // International Journal of Colorectal Disease;Sep2003, Vol. 18 Issue 5, p423
Background and aims. This prospective study compared jejunoileal length in patients with Crohn's disease (CD) and the general population to determine whether this parameter can be related to outcome and management of CD complications. Patients and methods. Small bowel (SB) length was measured...
- Granulomatous Enterocolitis Complicated by Osteomyelitis. Meltzer, Saul S. // American Journal of Gastroenterology;Jan1973, Vol. 59 Issue 1, p77
Osteomyelitis complicating granulomatous disease of the bowel is described in a case report. Bony complications of this disorder should be kept in mind since they may occur more commonly than has previously been appreciated.
- A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Ogura, Yasunori; Bonen, Denise K.; Inohara, Naohiro; Nicolae, Dan L.; Chen, Felicia F.; Ramos, Richard; Britton, Heidi; Moran, Thomas; Karaliuskas, Reda; Duerr, Richard H.; Achkar, Jean-Paul; Brant, Steven R.; Bayless, Theodore M.; Kirschner, Barbara S.; Hanauer, Stephen B.; Nunez, Gabriel; Cho, Judy H. // Nature;5/31/2001, Vol. 411 Issue 6837, p603
Presents a study which determined the association of a frameshift mutation in NOD2 caused by a cytosine insertion with Crohn's disease. Background on the idiopathic inflammatory bowel diseases; Methods used; Findings of the study.
- MULTIFACTORIAL DISEASE: Opening the flood gates? Alfred, Jane // Nature Reviews Genetics;Jul2001, Vol. 2 Issue 7, p486
Deals with two studies which identified linkage mapping of NOD2, a gene involved in Crohn disease (CD). Way by which the immune system might be involved in the etiology of CD; Association of CD to an allele of a chromosome 16 microsatellite marker; Mutations in the leucine-rich repeat region of...
- Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn’s disease patients. Braat, Henri; Stokkers, Pieter; Hommes, Tijmen; Cohn, Danny; Vogels, Esther; Pronk, Inge; Spek, Arnold; Kampen, Antoine; Deventer, Sander; Peppelenbosch, Maikel; Hommes, Daan // Journal of Molecular Medicine;Aug2005, Vol. 83 Issue 8, p601
The concept that mutations in germ-line encoded pattern recognition receptors with immune activating functions are associated with an increased incidence in Crohnâ€™s disease (CD) is gaining acceptance. Whether these mutations have similar or distinct effects on cellular physiology remains...
- Endoscopic Management of Inflammatory Bowel Disease. Modigliani, Robert // American Journal of Gastroenterology;Aug1994 Supplement, Vol. 89 Issue 8, pS53
Discusses the role of endoscopy in inflammatory bowel disease. Discussion on the basic endoscopic lesions on inflammatory bowel disease; Definition of the nature of stricture and mass lesions; Evaluation of patients with cholestasis; Analysis of endoscopic treatment of intestinal strictures in...
- Advances in the Inflammatory Bowel Diseases. // Gut;Jul2004, Vol. 53 Issue 7, p1058
The article presents that the conference for advances in the inflammatory bowel diseases will be held in Chicago, Illinois, from October 8-9, 2004.