Non-invasive evaluation of hepatic fibrosis: don't count your chickens before they're hatched
- Congenital Hepatic Fibrosis. Ghishan, Fayez K.; Younoszai, M. Kabir // American Journal of Gastroenterology;Apr1981, Vol. 75 Issue 4, p317
We present four pediatric patients with histologically proven congenital hepatic fibrosis. The patients had diverse manifestations. The first two patients were seven-year old identical twins who presented with hepatosplenomegaly and were found to have portal hypertension with esophageal varices....
- Congenital Hepatic Fibrosis in the Franches-Montagnes Horse Is Associated with the Polycystic Kidney and Hepatic Disease 1 (PKHD1) Gene. Drögemüller, Michaela; Jagannathan, Vidhya; Welle, Monika M.; Graubner, Claudia; Straub, Reto; Gerber, Vinzenz; Burger, Dominik; Signer-Hasler, Heidi; Poncet, Pierre-André; Klopfenstein, Stéphane; von Niederhäusern, Ruedi; Tetens, Jens; Thaller, Georg; Rieder, Stefan; Drögemüller, Cord; Leeb, Tosso // PLoS ONE;Oct2014, Vol. 9 Issue 10, p1
Congenital hepatic fibrosis has been described as a lethal disease with monogenic autosomal recessive inheritance in the Swiss Franches-Montagnes horse breed. We performed a genome-wide association study with 5 cases and 12 controls and detected an association on chromosome 20. Subsequent...
- Fibrosis. Vohr, Hans-Werner // Encyclopedic Reference of Immunotoxicology;2005, p242
A definition for fibrosis is presented. It refers to the formation of fibrous tissue. It is linked with systemic autoimmunity.
- Oral submucous fibrosis in India: Are we progressing?? Hebbar, P. B.; Sheshaprasad, R.; Gurudath, S.; Pai, A.; Sujatha, D. // Indian Journal of Cancer;Jul-Sep2014, Vol. 51 Issue 3, p222
Oral submucous fibrosis (OSMF) a condition first described in the 1950s in the modern literature still remains elusive of a cure. For many years this condition had been confined to countries like India, Pakistan, Bangladesh, etc., but now this condition is being reported from Western countries...
- Meta-analyses of FibroTest diagnostic value in chronic liver disease. Poynard, Thierry; Morra, Rachel; Halfon, Philippe; Castera, Laurent; Ratziu, Vlad; Imbert-Bismut, Francoise; Naveau, Sylvie; Thabut, Dominique; Lebrec, Didier; Zoulim, Fabien; Bourliere, Marc; Cacoub, Patrice; Messous, Djamila; Munteanu, Mona; de Ledinghen, Victor // BMC Gastroenterology;2007, Vol. 7, p40
Background: FibroTest (FT) is a biomarker of liver fibrosis initially validated in patients with chronic hepatitis C (CHC). The aim was to test two hypotheses, one, that the FT diagnostic value was similar in the three other frequent fibrotic diseases: chronic hepatitis B (CHB), alcoholic liver...
- Inhibition of Endothelin-1-Mediated Contraction of Hepatic Stellate Cells by FXR Ligand. Jiang Li; Kuruba, Ramalinga; Wilson, Annette; Xiang Gao; Yifei Zhang; Song Li // PLoS ONE;2010, Vol. 5 Issue 11, p1
Activation of hepatic stellate cells (HSCs) plays an important role in the development of cirrhosis through the increased production of collagen and the enhanced contractile response to vasoactive mediators such as endothelin-1 (ET-1). The farnesoid X receptor (FXR) is a member of the nuclear...
- Development and evaluation of a nurse-led transient elastography service for the staging of hepatic fibrosis in patients with suspected chronic liver disease. McCorry, R.B.; Palaniyappan, N.; Chivinge, A.; Kaye, P.; James, M.W.; Aithal, G.P. // QJM: An International Journal of Medicine;Aug2012, Vol. 105 Issue 8, p749
Background and Aims: Establishing the presence of fibrosis and cirrhosis is an essential step in the management of patients with chronic liver diseases (CLD). Liver stiffness measurement (LSM) based on transient elastography (TE) correlates well with the stages of liver fibrosis and has been...
- Corrections. // Gut;Aug2015, Vol. 64 Issue 8, p137
A correction to the article "Pathobiology of Liver Fibrosis Ã¢â‚¬ A Translational Success Story" by Y. A. Lee that was published in a 2015 issue of the periodical is presented.
- Corrections. // Gut;Aug2015, Vol. 64 Issue 8, p1337
A correction to the article "Pathobiology of Liver Fibrosis - A Translational Success Story" by Y. A. Lee that was published in a 2015 issue of the periodical is presented.