Tumour suppressor gene methylation and screening for lung cancer

Strtton, R.
January 2006
Thorax;Jan2006, Vol. 61 Issue 1, p33
Academic Journal
The article presents information about a study which focuses on the development of a screening tool for lung cancer. The study was conducted on three groups of women with different levels of lung cancer risk. The study examined the level of inhibitory methylation of specific tumour suppressor genes in these women. Under the study, plasma and sputum samples were taken from 74 never smokers, 121 current and former smokers and 56 patients who had undergone surgical resection of stage 1 lung cancer. The study shows that the detection of gene methylation in sputum could be developed as a screening test for lung cancer.


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