Using serum osteopontin to help identify pleural mesothelioma

Hui, C. K.
January 2006
Thorax;Jan2006, Vol. 61 Issue 1, p22
Academic Journal
The article reports on a study in which serum osteopontin levels were compared in 76 patients with surgically staged pleural mesothelioma, 69 patients with non-malignant asbestos disease, and 45 non-exposed controls. The study found no significant differences in mean (SE) serum levels of osteopontiri between the groups. This study indicates that tissue immunohistochemistry and serum ELISA assay for osteopontin are useful in distinguishing patients with pleural mesothelioma from those with non-malignant pulmonary disease who have been exposed to asbestos.


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