TITLE

Synthesis of �-Amino Alcohols by Regioselective Ring Opening of Epoxides with Aromatic Amines Catalyzed by Tin (II) Chloride [1]

AUTHOR(S)
Alam, M. Mujahid; Varala, Ravi; Enugala, Ramu; Adapa, Srinivas R.
PUB. DATE
March 2006
SOURCE
Letters in Organic Chemistry;Mar2006, Vol. 3 Issue 3, p187
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Tin (II) chloride dihydrate catalyses the nucleophilic ring opening of epoxide by aromatic amines leading to an efficient synthesis of �-amino alcohols in very good yields. The reactions are completely antistereoselective, highly regioselctive and proceed at ambient temperature which make this procedure particularly an alternative strategy for the synthesis of �-amino alcohols.
ACCESSION #
19718701

 

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