TITLE

The Fruitless Search for Schizophrenia Genes

AUTHOR(S)
Joseph, Jay
PUB. DATE
November 2004
SOURCE
Ethical Human Psychology & Psychiatry;Fall/Winter, Vol. 6 Issue 3, p167
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article reviews recent events in the continuing unsuccessful efforts to discover genes presumed to cause schizophrenia. Researchers and reviewers reporting these events usually downplay the continuing failures, and speak in glowing terms of discoveries they believe will occur in the future. However, schizophrenia molecular genetic research is based on the mistaken belief that previous kinship studies of families, twins, and adoptees have definitively established the genetic basis of schizophrenia. Thus, researchers rarely consider the possibility that they have found no schizophrenia genes because there are no schizophrenia genes. In this article, I argue that researchers should take a critical look into the original schizophrenia family, twin, and adoption research upon which they base their work. This might lead them to consider the possibility that the main premise of their work, that schizophrenia genes must exist, is false.
ACCESSION #
19573139

 

Related Articles

  • ASPECTOS GENÉTICOS DA ESQUIZOFRENIA REVISÃO DE LITERATURA. RANGEL, BÁRBARA LUIZA; DOS SANTOS, ADRIANA // UNINGÁ Review;Oct-Dec2013, Vol. 16 Issue 3, p27 

    Schizophrenia is a complex mental disease. The risk for the development of the disease is 1% in the general population and increases with the degree of relatedness. The etiology of schizophrenia is still unclear and currently many researches are focused in this area. The aim of this review is to...

  • How to provide support for teens with mental illness.  // Asian Pacific Post;2/9/2012, p5 

    The article presents various ways by which an individual can provide support to someone who has been diagnosed with schizophrenia or another mental illness.

  • Validation in mental health treatment. McLean, Richard // Australian Nursing Journal;Dec2009/Jan2010, Vol. 17 Issue 6, p33 

    The author ponders on the provision of mental health services to people with schizophrenia in Australia. He describes how schizophrenics cope with their mental illness. He proposes an approach that psychiatrists should consider when dealing with their schizophrenic patients. The author opines...

  • Schizophrenia researchers striving for early detection and intervention. Stephenson, Joan; Stephenson, J // JAMA: Journal of the American Medical Association;5/26/99, Vol. 281 Issue 20, p1877 

    Focuses on efforts to identify early signs of schizophrenia in high-risk individuals and to develop interventions aimed at delaying its onset or reducing severity. Diagnosis, treatment delays; Early signs; Research efforts in Australia.

  • Aggressive behaviour in patients with schizophrenia is associated with catechol-O-methyltransferase genotype. Jones, G.; Zammit, S.; Norton, N.; Hamshere, M. L.; Jones, S. J.; Milham, C.; Sanders, R. D.; McCarthy, G. M.; Jones, L. A.; Cardno, A. G.; Gray, M.; Murphy, K. C.; Owen, M. J. // British Journal of Psychiatry;Oct2001, Vol. 179, p351 

    Background: Evidence exists for an association between aggression and schizophrenia. Although the aetiology of aggression is multifactorial, three studies have reported associations between polymorphisms of the catechol-O-methyltransferase (COMT) gene and aggression in...

  • PORTRAIT OF MY SON'S MENTAL ILLNESS. Kelly, Marsha Boone // Essence (Time Inc.);Apr2005, Vol. 35 Issue 12, p146 

    Relates an experience in having a son with schizophrenia. Explanation on schizophrenia; Information on the unusual behavior of her son; Facts about the clubhouse day program, a community-based options for people with schizophrenia and other forms of mental illness.

  • Burden of care and general health in families of patients with schizophrenia. Gutiérrez-Maldonado, José; Caqueo-Urízar, Alejandra; Kavanagh, David J.; Gutiérrez-Maldonado, José; Caqueo-Urízar, Alejandra // Social Psychiatry & Psychiatric Epidemiology;Nov2005, Vol. 40 Issue 11, p899 

    Background: De-institutionalization of psychiatric patients has led to a greater emphasis on family management in the community, and family members are often overwhelmed by the demands that caring for a patient with schizophrenia involves. Most studies of family burden in...

  • Descriptive richness and abstract theorizing pertaining to schizophrenic disorders. TRAFIMOW, DAVID // Dialogues in Philosophy, Mental & Neuro Sciences;Jun2012, Vol. 5 Issue 1, p29 

    The author comments on a paper which explored the problems in diagnosing schizophrenia. The author questions the recommendation by the paper for more schizophrenia research to be devoted to understanding relevant subjective experiences of schizophrenics. The author highlights the failure of...

  • Behavioural vigilance in schizophrenia. Evidence for hyperattentional processing. Mar, Corinne M.; Smith, David A.; Sarter, Martin; Mar, C M; Smith, D A; Sarter, M // British Journal of Psychiatry;Dec96, Vol. 169, p781 

    Background: Despite 30 years of research, some surprisingly fundamental gaps remain in our understanding of schizophrenic input dysfunctions.Method: In a provisional test of a 'hyperattention' hypothesis, schizophrenic patients and control subjects performed a...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics